Biochimica et Biophysica Acta 2013-09-01

Phase diagram of a 4-component lipid mixture: DSPC/DOPC/POPC/chol.

Tatyana M Konyakhina, Jing Wu, James D Mastroianni, Frederick A Heberle, Gerald W Feigenson

文献索引：Biochim. Biophys. Acta 1828(9) , 2204-14, (2013)

全文：HTML全文

摘要

We report the first 4-component phase diagram for the lipid bilayer mixture, DSPC/DOPC/POPC/chol (distearoylphosphatidylcholine/dioleoylphosphatidylcholine/1-palmitoyl, 2-oleoylphosphatidylcholine/cholesterol). This phase diagram, which has macroscopic Ld+Lo phase domains, clearly shows that all phase boundaries determined for the 3-component mixture containing DOPC transition smoothly into the boundaries for the 3-component mixture containing POPC, which has nanoscopic phase domains of Ld+Lo. Our studies start from two published ternary phase diagrams, and show how these can be combined into a quaternary phase diagram by study of a few hundred samples of intermediate compositions. Copyright © 2013 Elsevier B.V. All rights reserved.

相关化合物

  • 2-油酰-1-棕榈锡甘...
  • DL-α-磷脂酰胆碱,...
  • 1,2-二[反式-9-十八...
  • 1,2-二油酰基-sn-甘...
  • 二硬脂酰磷脂酰胆碱

相关文献：

Characterizing the structure of lipodisq nanoparticles for membrane protein spectroscopic studies.

2015-01-01

[Biochim. Biophys. Acta 1848(1 Pt B) , 329-33, (2015)]

Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections.

2015-05-01

[Pharm. Res. 32(5) , 1546-56, (2015)]

The cytolytic activity of vaginolysin strictly depends on cholesterol and is potentiated by human CD59.

2015-01-01

[Toxins (Basel.) 7(1) , 110-28, (2015)]

Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells.

2014-10-01

[Nature Chemistry 6(10) , 885-92, (2014)]

Role of polyol moiety of amphotericin B in ion channel formation and sterol selectivity in bilayer membrane.

2015-09-01

[Bioorg. Med. Chem. 23 , 5782-8, (2015)]

更多文献...