Bioscience, Biotechnology, and Biochemistry 2000-08-01

Synthesis of the spirosuccinimide moiety of Asperparaline A.

S Tanimori, K Fukubayashi, M Kirihata

文献索引：Biosci. Biotechnol. Biochem. 64(8) , 1758-60, (2000)

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摘要

2,6,6-Trimethyl-2-azaspiro[4.4]nonane-1,3-dione (9), a spirosuccinimide moiety of asperparaline A (1), was synthesized by starting from 2,2-dimethylcyclopentanone (4) via trinitrile 6 in five steps in a moderate yield. This conversion establishes a model study for synthesis of the spirosuccinimide moiety of asperparaline A (1).

相关化合物

  • 2,2-二甲基环戊酮

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