Chemical modification of neamine.
T Suami, S Nishiyama, Y Ishikawa, S Katsura
文献索引:Oncogene 21(28) , 4462-70, (2002)
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摘要
The aminocyclitol antibiotic neamine has been modified chemically by removing one or two hydroxyl groups from the 2-deoxystreptamine moiety to give 5- and 6- deoxyneamines (5 and 10), as well as 5,6-dideoxyneamine (15). Their antimicrobial activities were determined against several microorganisms, including kanamycin-resistant strains.
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