Expanding the chemical diversity of spirooxindoles via alkylative pyridine dearomatization.
Chunhui Dai, Bo Liang, Corey R J Stephenson
文献索引：Beilstein J. Org. Chem. 8 , 986-93, (2012)
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摘要
A mild and practical synthesis of spirooxindole [1,3]oxazino derivatives from N-substituted isatins and 1,3-dicarbonyl compounds with pyridine derivatives is reported. The reactions provided good to excellent yields. Further exploration of the molecular diversity of these compounds is demonstrated through Diels-Alder reactions.
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