Biotechnology Letters 2003-03-01

Improving lipase-catalyzed enantioselective ammonolysis of phenylglycine methyl ester in organic solvent by in situ racemization.

Wei Du, Minhua Zong, Yong Guo, Dehua Liu

文献索引：Biotechnol. Lett. 25(6) , 461-4, (2003)

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摘要

Lipase-catalyzed enantioselective ammonolysis of phenylglycine methyl ester was processed by in situ racemization with ammonium carbamate as the acyl acceptor. Using 1 mM benzaldehyde or 0.6 mM chloropyridoxal as the racemizing catalyst, 80% substrate conversion with an enantiomeric excess of the product of 95% were achieved at 20 degrees C after 7 h reaction.

相关化合物

  • D-苯甘氨酸甲酯盐酸...

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