Toxicon 1988-01-01

Sarafotoxins S6: several isotoxins from Atractaspis engaddensis (burrowing asp) venom that affect the heart.

C Takasaki, N Tamiya, A Bdolah, Z Wollberg, E Kochva

文献索引:Toxicon 26 , 543, (1988)

全文:HTML全文

摘要

Three isotoxins, named sarafotoxins S6a1, S6b and S6c, with strong cardiotoxic activity were isolated from the venom of a snake, Atractaspis engaddensis. All three sarafotoxins are homologous peptides (four or less than four residue replacements) consisting of 21 amino acid residues. Their structure and activity are novel among snake venom components.


相关化合物

  • 角蝰毒素S6b

相关文献:

Sarafotoxin, a novel vasoconstrictor peptide: phosphoinositide hydrolysis in rat heart and brain.

1988-10-14

[Science 242 , 268, (1988)]

Role of the endothelin axis and its antagonists in the treatment of cancer.

2011-05-01

[Br. J. Pharmacol. 163 , 220-233, (2011)]

LPS fromPorphyromonas gingivalisincreases the sensitivity of contractile response mediated by endothelin-B (ETB) receptors in cultured endothelium-intact rat coronary arteries

2010-01-01

[Vascul. Pharmacol. 53 , 250-257, (2010)]

Functional and molecular characterization of the endothelin system in retinal arterioles.

2009-07-01

[Invest. Ophthalmol. Vis. Sci. 50 , 3329-3336, (2009)]

Endothelin ET(B) receptors in arteries and veins: multiple actions in the vein.

2009-06-01

[J. Pharmacol. Exp. Ther. 329 , 875-881, (2009)]

更多文献...