Organic Letters 2001-09-06

Solid-phase synthesis of 1,7-disubstituted-1,3,5-triazepane-2,4-diones.

Y Yu, J M Ostresh, R A Houghten

文献索引：Org. Lett. 3(18) , 2797-9, (2001)

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摘要

[reaction: see text]. The solid-phase synthesis of 1,7-disubstituted-1,3,5-triazepane-2,4-diones from resin-bound amino acids is described. The exhaustive reduction of solid-support bound amides with borane afforded the requisite secondary amines, which following treatment with phenyl isocyanatoformate and cleavage, provided the corresponding triazepane-2,4-diones.

相关化合物

  • 异氰酸基甲酸苯酯

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