Molecular and Biochemical Parasitology 2012-08-01

Biochemical and molecular characterization of the pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase fromToxoplasma gondii

Miryam Andrea Hortua Triana, My-Hang Huynh, Manuel F. Garavito, Barbara A. Fox, David J. Bzik, Vern B. Carruthers, Monika Löffler, Barbara H. Zimmermann, Miryam Andrea Hortua Triana, My-Hang Huynh, Manuel F Garavito, Barbara A Fox, David J Bzik, Vern B Carruthers, Monika Löffler, Barbara H Zimmermann

文献索引：Mol. Biochem. Parasitol. 184(2) , 71-81, (2012)

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摘要

Graphical abstract Toxoplasma gondii dihydroorotate dehydrogenase is an essential mitochondrial enzyme that exhibits inhibitor sensitivities distinct from those of the human and Plasmodium falciparum enzymes.

相关化合物

  • 乳清酸
  • 核苷酸
  • D-氢化乳清酸

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