Antihypertensive (2-aminoethyl)thiourea derivatives. 2.

J W Tilley, H Ramuz, F Hefti, M Gerold

文献索引：J. Med. Chem. 23(12) , 1438-9, (1980)

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摘要

Starting with 2,6-dichlorophenyl isothiocyanate, 1-(2-aminoethyl)-2-cyano-3-(2,6-dichlorophenyl)guanidine (2) was prepared in three steps. In contrast to the corresponding thiourea 1, this compound was essentially inactive as an antihypertensive agent.