Organic & Biomolecular Chemistry 2013-09-21

Urea-catalyzed construction of oxazinanes.

Andrea M Hardman, Sonia S So, Anita E Mattson

文献索引：Org. Biomol. Chem. 11(35) , 5793-7, (2013)

全文：HTML全文

摘要

Highly functionalized oxazinanes are efficiently prepared through urea-catalyzed formal [3 + 3] cycloaddition reactions of nitrones and nitrocyclopropane carboxylates. The reaction system is general with respect to both the nitrocyclopropane carboxylates and nitrones enabling the preparation of a large family of oxazinanes, typically in high yield. This method affords access to enantioenriched oxazinane products through chirality transfer from enantioenriched nitrocyclopropane carboxylates.

相关化合物

  • Mattson Boronate...
  • Mattson Difluorob...

相关文献：

Urea-catalyzed N-H insertion-arylation reactions of nitrodiazoesters.

2014-06-06

[J. Org. Chem. 79(11) , 4832-42, (2014)]

Arylation of diazoesters by a transient N-H insertion organocascade.

2013-10-18

[Angew. Chem. Int. Ed. Engl. 52(43) , 11317-20, (2013)]

Internal Lewis acid assisted ureas: tunable hydrogen bond donor catalysts.

2013-05-14

[Chem. Commun. (Camb.) 49 , 4289-4291, (2013)]

Boronate urea activation of nitrocyclopropane carboxylates.

2012-01-20

[Org. Lett. 14(2) , 444-7, (2012)]

Internal Lewis acid assisted hydrogen bond donor catalysis.

2011-02-18

[Org. Lett. 13(4) , 716-9, (2011)]

更多文献...