Tetrahedron Letters
2011-04-01
Efficient microwave-assisted one-pot preparation of angular 2,2-dimethyl-2H-chromone containing compounds.
Ting Zhou, Qian Shi, KuoHsing Lee
文献索引:Tetrahedron Lett. 51(33) , 4382-4386, (2010)
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摘要
A novel and efficient microwave-assisted one-pot reaction was developed to synthesize angular 2,2-dimethyl-2H-chromone containing compounds, which is the first and key step in the synthesis of potent DCK and DCP anti-HIV agents. The newly developed microwave synthesis conditions dramatically shortened the reaction time from 2 days to 4 hours with improved yields.
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