Turmeric (Curcuma longa L.) volatile oil inhibits key enzymes linked to type 2 diabetes.
P C Lekshmi, Ranjith Arimboor, P S Indulekha, A Nirmala Menon
文献索引:Int. J. Food Sci. Nutr. 63(7) , 832-4, (2012)
全文:HTML全文
摘要
Anti-diabetic capacity of Curcuma longa volatile oil in terms of its ability to inhibit glucosidase activities was evaluated. Turmeric volatile oils inhibited glucosidase enzymes more effectively than the reference standard drug acarbose. Drying of rhizomes was found to enhance α-glucosidase (IC₅₀ = 1.32-0.38 μg/ml) and α-amylase (IC₅₀ = 64.7-34.3 μg/ml) inhibitory capacities of volatile oils. Ar-Turmerone, the major volatile component in the rhizome also showed potent α-glucosidase (IC₅₀ = 0.28 μg) and α-amylase (IC₅₀ = 24.5 μg) inhibition.
相关化合物
相关文献:
2002-05-01
[Int. J. Mol. Med. 9(5) , 481-4, (2002)]
2004-08-01
[Int. J. Mol. Med. 14(2) , 253-6, (2004)]
2001-10-01
[Arch. Pharm. Res. 24(5) , 424-6, (2001)]
2009-02-28
[BMB Rep. 42(2) , 96-100, (2009)]
2012-10-01
[Neurochem. Int. 61(5) , 767-77, (2012)]