Journal of the American Chemical Society
2003-07-02
C-H activation/borylation/oxidation: a one-pot unified route to meta-substituted phenols bearing ortho-/para-directing groups.
Robert E Maleczka, Feng Shi, Daniel Holmes, Milton R Smith
文献索引:J. Am. Chem. Soc. 125 , 7792, (2003)
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摘要
An efficient one-pot C-H activation/borylation/oxidation protocol for the preparation of phenols is described. This method is particularly attractive for the generation of meta-substituted phenols bearing ortho-/para-directing groups, as such substrates are difficult to access by other phenol syntheses.