Antiviral activity of 2-amino-4,4alpha-dihydro-4alpha-7-dimethyl-3H-phenoxazine-3-one on poliovirus.
Akiko Iwata, Teruhide Yamaguchi, Kouei Sato, Ryutaro Izumi, Akio Tomoda
文献索引:Tohoku J. Exp. Med. 200(3) , 161-5, (2003)
全文:HTML全文
摘要
2-Amino-4,4alpha-dihydro-4alpha-7-dimethyl-3H-phenoxazine-3-one (Phx), which was produced by the reaction of bovine hemoglobin with 2-amino-5-methylphenol, inhibited the proliferation of poliovirus in Vero cells between 0.25 microg/ml and 2 microg/ml with maximal antiviral acitivity at 1 microg/ml. These results suggest that Phx may be useful to prevent the proliferation of poliovirus infection.
相关化合物
相关文献:
2000-12-01
[Tohoku J. Exp. Med. 192(4) , 301-12, (2000)]
1992-10-27
[Biochim. Biophys. Acta 1117(3) , 306-14, (1992)]
2001-04-23
[Bioorg. Med. Chem. Lett. 11(8) , 1057-8, (2001)]
2007-06-01
[Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 67(2) , 550-8, (2007)]
Synthesis,structural characterization and catalytic activity study of Mn(II), Fe(III), Ni(II), Cu(II) and Zn(II) complexes of quinoxaline-2-carboxalidine-2-amino-5-methylphenol: Crystal structure of the nickel (II) complex. Sebastian M, et al.
[Polyhedron 29(15) , 3014-3020, (2010)]