Journal of Organic Chemistry 2001-06-15

Rapid homogeneous-phase Sonogashira coupling reactions using controlled microwave heating.

M Erdélyi, A Gogoll

文献索引：J. Org. Chem. 66(12) , 4165-9, (2001)

全文：HTML全文

摘要

A microwave-enhanced, rapid and efficient homogeneous-phase version of the Sonogashira reaction is presented. It has been applied to the coupling of aryl iodides, bromides, triflates, and aryl chloride, as well as pyridine and thiophene derivatives with trimethylsilylacetylene. Excellent yields (80-95%) for substrates containing a large variety of substituents in different positions are obtained in 5-25 min.

相关化合物

  • 2-碘噻吩

相关文献：

Cross-coupling reactions of alkenylsilanolates. Investigation of the mechanism and identification of key intermediates through kinetic analysis.

2004-04-21

[J. Am. Chem. Soc. 126(15) , 4876-82, (2004)]

Stereospecific preparation of (Z)- and (E)-2,3-difluoro-3-stannylacrylic ester synthons and a new, efficient stereospecific route to (Z)- and (E)-2,3-difluoroacrylic esters.

2005-12-23

[J. Org. Chem. 70(26) , 10743-6, (2005)]

Near ultraviolet photochemistry of 2-bromo- and 2-iodothiophene: Revealing photoinduced ring opening in the gas phase?

2015-06-14

[J. Chem. Phys. 142 , 224303, (2015)]

Thin conductive coatings formed by plasma polymerization of 2-iodothiophene. Kruse A, et al.

[Surf. Coat. Technol. 59(1) , 359-64, (1993)]

更多文献...