Organic Letters 2000-10-05

Efficient asymmetric synthesis of radicicol dimethyl ether: a novel application of ring-forming olefin metathesis.

R M Garbaccio, S J Danishefsky

文献索引：Org. Lett. 2 , 3127, (2000)

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摘要

A concise, stereospecific synthesis of radicicol dimethyl ether is presented. The strategy relies on a convergent three-stage assembly of the 14-membered lactone which has, as a key transformation, a novel ring-forming metathesis reaction utilizing a vinyl epoxide.

相关化合物

  • (R)-3-羟基丁酸甲酯

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