Organic Letters 2013-10-18

N-bromoimide/DBU combination as a new strategy for intermolecular allylic amination.

Ying Wei, Fushun Liang, Xintong Zhang

文献索引：Org. Lett. 15(20) , 5186-9, (2013)

全文：HTML全文

摘要

Allylic amination reactions of alkenes, with an NBP (N-bromophthalimide) or NBS (N-bromosuccinimide)/DBU combination, were developed, in which both internal and external nitrogen nucleophiles can be installed directly. Dual activation of NBS or NBP by DBU leads to more electrophilic bromine and more nucleophilic nitrogen atoms simultaneously. This protocol may provide a novel and complementary access to allylic amination under mild conditions.

相关化合物

  • N-溴酞亚胺

相关文献：

Enantioselective synthesis of multisubstituted biaryl skeleton by chiral phosphoric acid catalyzed desymmetrization/kinetic resolution sequence.

2013-03-13

[J. Am. Chem. Soc. 135(10) , 3964-70, (2013)]

Titrimetric determination of acetylenic hyponotics using organic brominating agents.

1988-04-22

[Pharm. Weekbl. Sci. 10(2) , 90-2, (1988)]

Colorimetric and titrimetric assay of isoniazid.

1992-06-01

[J. Pharm. Biomed. Anal. 10(6) , 421-6, (1992)]

C2-symmetric cyclic selenium-catalyzed enantioselective bromoaminocyclization.

2013-01-30

[J. Am. Chem. Soc. 135(4) , 1232-5, (2013)]

Site-selective bromination of vancomycin.

2012-04-11

[J. Am. Chem. Soc. 134(14) , 6120-3, (2012)]

更多文献...