Catalytic enantioselective thioester aldol reactions that are compatible with protic functional groups.

Derek Magdziak, Gojko Lalic, Hong Myung Lee, Kevin C Fortner, Allen D Aloise, Matthew D Shair

文献索引：J. Am. Chem. Soc. 127 , 7284, (2005)

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摘要

This communication reports highly enantioselective and diastereoselective methyl malonic acid half thioester (MeMAHT) aldol reactions that are compatible with protic functional groups and enolizable aldehydes, affording syn S-phenyl thiopropionates.