Perspectives of CCK antagonists in pancreatic research. Part II. Experimental studies.
T Takács, A Pap
文献索引:Int. J. Pancreatol. 10(1) , 1-8, (1991)
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摘要
In this article, the effects of different classes of cholecystokinin (CCK) receptor antagonists in CCK-related physiological processes of the pancreas have been discussed. Both glutaramic acid derivatives and natural (benzodiazepine) analogs are potent, competitive antagonists of peripheral CCK receptors. These compounds thus provide a powerful tool for investigating the physiological and pharmacological actions of CCK in the gastrointestinal system, and have already clarified the role of CCK in pancreatic secretion and trophism or growth.
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