Chemical & Pharmaceutical Bulletin 2003-04-01

Synthesis of alpha,alpha-dibromo esters as precursors of ynolates.

Mitsuru Shindo, Yusuke Sato, Ryoko Koretsune, Takashi Yoshikawa, Kenji Matsumoto, Kotaro Itoh, Kozo Shishido

文献索引：Chem. Pharm. Bull. 51(4) , 477-78, (2003)

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摘要

Aliphatic alpha,alpha-dibromo esters, precursors of ynolates, were synthesized via bromination of lithium alpha-bromo ester enolates with 1,2-dibromotetrafluoroethane in good yields. alpha-Trimethylsilyl-alpha,alpha-dibromo esters were synthesized via radical bromination.

相关化合物

  • 2-溴己酸乙酯　
  • 三甲基硅乙酸乙酯

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