Investigational New Drugs
1996-01-01
A simplified and efficient synthesis of 5,10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF).
E C Taylor, R Chaudhari, K Lee
文献索引:Invest. New Drugs 14(3) , 281-5, (1996)
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摘要
A new and extremely efficient synthesis of DDATHF from 4-vinylbenzoic acid and bromomalondialdehyde as precursors has been developed which proceeds in 48% overall yield.
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