Carbohydrate Research 1998-12-21

Synthesis and biological evaluation of ureido and thioureido derivatives of 2-amino-2-deoxy-D-glucose and related aminoalcohols as N-acetyl-beta-D-hexosaminidase inhibitors.

C Tournaire-Arellano, S Y Hage, P Valès, R Caujolle, A Sanon, C Bories, P M Loiseau

文献索引：Carbohydr. Res. 314(1-2) , 47-63, (1998)

全文：HTML全文

摘要

Ureido and thioureido derivatives of 2-acetamido-2-deoxy-beta-D-glucose, 1-amino-1-deoxy-D-glucitol and 2-(2-aminoethoxy)ethanol were prepared as N-acetyl-beta-D-hexosaminidase (NAHase) inhibitors and were evaluated on Trichomonas vaginalis NAHase. Although none showed complete inhibition of the enzyme at 100 microM, 1-amino-1-deoxy-D-glucitol derivatives acted as competitive inhibitors of the NAHase of T. vaginalis.

相关化合物

  • 二甘醇胺

相关文献：

The Effect of Surface Modification of Aligned Poly-L-Lactic Acid Electrospun Fibers on Fiber Degradation and Neurite Extension.

2015-01-01

[PLoS ONE 10 , e0136780, (2015)]

Design of quantum dot-conjugated lipids for long-term, high-speed tracking experiments on cell surfaces.

2008-11-12

[J. Am. Chem. Soc. 130(45) , 15054-62, (2008)]

Morpholine degradation pathway of Mycobacterium aurum MO1: direct evidence of intermediates by in situ 1H nuclear magnetic resonance.

1998-01-01

[Appl. Environ. Microbiol. 64(1) , 153-8, (1998)]

更多文献...