Il Farmaco 2002-08-01

Synthesis and antimicrobial activity of new adamantane derivatives III.

Andrzej Orzeszko, Beata Kamińska, Bohdan J Starościak

文献索引：Il Farmaco 57(8) , 619-24, (2002)

全文：HTML全文

摘要

Some novel ester imides synthesised from trimellitic acid anhydride and 1-adamantanol or 2-adamantanol, were tested as antimicrobial compounds. Unfortunately, these agents showed a modest antibacterial activity (MIC > 6 microg/ml). However, a comparison of these N-substituted adamantylester imides with the series published previously, indicated that the incorporation of L-alanine and L-phenylalanine into the phthalimide moiety was the best choice regardless of the series and leads to antimicrobial activity against Staphylococcus aureus strains.

相关化合物

  • 2-金刚烷醇

相关文献：

Low-temperature X-ray structural studies of the ester and ether derivatives of cis- and trans-4-tert-butyl cyclohexanol and 2-adamantanol: application of the variable oxygen probe to determine the relative sigma-donor ability of C-H and C-C bonds.

2003-09-07

[Org. Biomol. Chem. 1(17) , 3094-101, (2003)]

Regioselective hydroxylation of adamantane by Streptomyces griseoplanus cells.

2006-07-01

[Appl. Microbiol. Biotechnol. 71(4) , 502-4, (2006)]

Photoaffinity labeling of cytochrome P450 2B4: capture of active site heme ligands by a photocarbene.

1994-01-25

[Biochemistry 33(3) , 807-17, (1994)]

Thermal properties of adamantanol derivatives and their beta-cyclodextrin complexes in phosphatidylcholine bilayers.

1998-01-01

[Life Sci. 62(20) , 1901-10, (1998)]

更多文献...