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对二甲氨基苯甲醛

对二甲氨基苯甲醛用途

p-Dimethylaminobenzaldehyde (4-Dimethylaminobenzaldehyde) 是多见于 Ehrlich's 和 Kovac's 试剂中用于检测吲哚的一种含胺和醛的化合物。

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对二甲氨基苯甲醛名称

[ CAS 号 ]:
100-10-7

[ 中文名 ]:
对二甲胺基苯甲醛

[ 英文名 ]:
p-Dimethylaminobenzaldehyde

[中文别名 ]:

[英文别名 ]:

N,N-Dimethyl-p-aminobenzaldehyde
p-(N,N-Dimethylamino)benzaldehyde
p-N,N-Dimethylaminobenzaldehyde
Ehrlichs
p-dimethylaminobenzaldehyde
EINECS 202-819-0
EHRICH'S REAGENT
N,N-Dimethyl-4-aminobenzaldehyde
Para-Dimethylaminobenzaldehyde
p-Formyldimethylaniline

对二甲氨基苯甲醛生物活性

[ 描述 ]:

p-Dimethylaminobenzaldehyde (4-Dimethylaminobenzaldehyde) 是多见于 Ehrlich's 和 Kovac's 试剂中用于检测吲哚的一种含胺和醛的化合物。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Axel Ehmann, et al. The van URK-Salkowski reagent — a sensitive and specific chromogenic reagent for silica gel thin-layer chromatographic detection and identification of indole derivatives. Journal of Chromatography A. Volume 132, Issue 2, 11 February 1977, Pages 267-276.

对二甲氨基苯甲醛物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
176-177 ºC (17 mmHg)

[ 熔点 ]:
72-75 °C(lit.)

[ 分子式 ]:
C₉H₁₁NO

[ 分子量 ]:
149.190

[ 闪点 ]:
164 ºC

[ 精确质量 ]:
149.084061

[ PSA ]:
20.31000

[ LogP ]:
1.81

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.0±0.5 mmHg at 25°C

[ 折射率 ]:
1.596

[ 储存条件 ]:
2-8°C

[ 稳定性 ]:
Stable, but light sensitive. Incompatible with bases, strong oxidizing agents.

[ 水溶解性 ]:
0.3 g/L (20 ºC)

对二甲氨基苯甲醛MSDS

对二甲氨基苯甲醛毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CU5775000

CHEMICAL NAME :: Benzaldehyde, p-(dimethylamino)-

CAS REGISTRY NUMBER :: 100-10-7

LAST UPDATED :: 199710

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C9-H11-N-O

MOLECULAR WEIGHT :: 149.21

WISWESSER LINE NOTATION :: VHR DN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 620 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HINEL* Hine Laboratories Reports. (San Francisco, CA) Volume(issue)/page/year: AF33(657)-11756,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533441

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - ataxia

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533441 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1800 mg/kg/9D-I

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Related to Chronic Data - death

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533441 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80179 No. of Facilities: 622 (estimated) No. of Industries: 8 No. of Occupations: 13 No. of Employees: 6871 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80179 No. of Facilities: 1897 (estimated) No. of Industries: 7 No. of Occupations: 20 No. of Employees: 23642 (estimated) No. of Female Employees: 15264 (estimated)

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对二甲氨基苯甲醛安全信息

[ 符号 ]:

GHS02, GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H226-H290-H314-H332-H335

[ 警示性声明 ]:
P210-P261-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R22;R52/53

[ 安全声明 (欧洲) ]:
S7-S16-S24/25-S26-S61-S45-S39-S36/37/39

[ 危险品运输编码 ]:
UN 2920 8/PG 2

[ WGK德国 ]:
1

[ RTECS号 ]:
CU5775000

[ 包装等级 ]:
I; II; III

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2912210000

对二甲氨基苯甲醛合成路线

对二甲氨基苯甲醛上下游产品

对二甲氨基苯甲醛上游产品

对二甲氨基苯甲醛下游产品

对二甲氨基苯甲醛制备

以N,N-二甲基苯胺为原料，可采用两种方法生产。（1）以乌洛托品反应生成亚甲基-N,N-二甲氨基苄胺，转位生成N,N-二甲基亚苄甲胺，然后水解得产品。（2）与二甲基甲酰胺在三氯氧磷存在下反应。另外，还有一种实验室制备方法是，以N,N-二甲基苯胺、亚硝酸钠、甲醛为原料制备。

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对二甲氨基苯甲醛海关

[ 海关编码 ]: 2922399090

[ 中文概述 ]:
2922399090 其他氨基醛、氨基酮及其盐（包括氨基醌及其盐，但含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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更多文献

对二甲氨基苯甲醛

对二甲氨基苯甲醛用途

对二甲氨基苯甲醛名称

对二甲氨基苯甲醛生物活性

对二甲氨基苯甲醛物理化学性质

对二甲氨基苯甲醛MSDS

详细MSDS(安全技术说明书)

对二甲氨基苯甲醛毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

对二甲氨基苯甲醛安全信息

对二甲氨基苯甲醛合成路线

详细合成路线

对二甲氨基苯甲醛上下游产品

对二甲氨基苯甲醛上游产品

对二甲氨基苯甲醛下游产品

对二甲氨基苯甲醛制备

对二甲氨基苯甲醛海关

对二甲氨基苯甲醛文献

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