DESMOSINE STANDARD

[ 分子式 ]:
C₂₄H₄₀ClN₅O₈

[ 分子量 ]:
562.05600

[ 精确质量 ]:
561.25700

[ PSA ]:
257.16000

详细MSDS(安全技术说明书)

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

Urinary desmosine excretion is inversely correlated with the extent of emphysema in patients with chronic obstructive pulmonary disease.

Int. J. Biochem. Cell Biol. 34 , 594-604, (2002)

An enhanced proteolysis of lung interstitium is key event in the pathogenesis of emphysema, a major constituent of chronic obstructive pulmonary disease. To assess whether urinary desmosine and/or hyd...

Elastin degradation and calcification in an abdominal aorta injury model: role of matrix metalloproteinases.

Circulation 110 , 3480-3487, (2004)

Elastin calcification is a widespread feature of vascular pathology, and circumstantial evidence exists for a correlation between elastin degradation and calcification. We hypothesized that matrix met...

Aluminum chloride pretreatment of elastin inhibits elastolysis by matrix metalloproteinases and leads to inhibition of elastin-oriented calcification.

Am. J. Pathol. 159 , 1981-1986, (2001)

Calcification of elastin occurs in many pathological cardiovascular diseases including atherosclerosis. We have previously shown that purified elastin when subdermally implanted in rats undergoes seve...

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