恩普氨酯
恩普氨酯名称
[ CAS 号 ]:
10087-89-5
[ 中文名 ]:
恩普氨酯
[ 英文名 ]:
Enpromate
[英文别名 ]:
- Enpromatum [INN-Latin]
- Empromate
- ENPROMATE
- Acetylenic carbamate
- Empromato [INN-Spanish]
- 1,1-Diphenyl-2-propynyl cyclohexylcarbamate
- 1,1-Diphenyl-2-propynylcyclophosphamide
- Enpromate [USAN:INN]
- 1,1-Diphenyl-2-propinyl-cyclohexylcarbamat
恩普氨酯物理化学性质
[ 密度 ]:
1.14g/cm3
[ 沸点 ]:
476.9ºC at 760mmHg
[ 熔点 ]:
160.5°C
[ 分子式 ]:
C22H23NO2
[ 分子量 ]:
333.42400
[ 闪点 ]:
242.2ºC
[ 精确质量 ]:
333.17300
[ PSA ]:
38.33000
[ LogP ]:
5.01320
[ 蒸汽压 ]:
2.94E-09mmHg at 25°C
[ 折射率 ]:
1.595
恩普氨酯毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GU7175000
- CHEMICAL NAME :
- Cyclohexanecarbamic acid, 1,1-diphenyl-2-propynyl ester
- CAS REGISTRY NUMBER :
- 10087-89-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 13
- MOLECULAR FORMULA :
- C22-H23-N-O2
- MOLECULAR WEIGHT :
- 333.46
- WISWESSER LINE NOTATION :
- L6TJ AMVOXR&R&1U1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 374 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- >250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1690 mg/kg/27W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 31500 mg/kg/67W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Cardiac - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1925 mg/kg/11W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 13600 mg/kg/40W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Cardiac - tumors Gastrointestinal - tumors
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Rodent - rat Liver
- DOSE/DURATION :
- 10 umol/L
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 3,11,1981
恩普氨酯安全信息
[ 海关编码 ]:
2924299090
恩普氨酯上下游产品
恩普氨酯上游产品
恩普氨酯下游产品
恩普氨酯海关
[ 海关编码 ]: 2924299090
[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 包装
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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相关化合物
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