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咪唑-2-甲醛

咪唑-2-甲醛用途

1H-咪唑-2-甲醛是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

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咪唑-2-甲醛名称

[ CAS 号 ]:
10111-08-7

[ 中文名 ]:
2-咪唑甲醛

[ 英文名 ]:
2-Acetlimidazole

[中文别名 ]:

咪唑-2-甲醛

[英文别名 ]:

2-Formylimidazole
1H-2-imidazolecarbaldehyde
imidazole 2-carboxaldeyde
2-FORMAYLIMIDAZOLE
2-imidazolylcarboxaldehyde
1H-Imidazole-2-carboxaldehyde
2-1H-imidazolcarbaldehyde
Imidazole-2-carbaldehyde
1H-Imidazole-2-carbaldehyde
Imidazole-2-carboxaldehyde

咪唑-2-甲醛生物活性

[ 描述 ]:

1H-咪唑-2-甲醛是一种生物化学试剂,可作为生物材料或有机化合物用于生命科学相关研究。

[ 相关类别 ]:

研究领域 >> 其他

[体外研究]

咪唑-2-甲醛是一种新型蛋白酪氨酸磷酸酶 1B(PTP1B)抑制剂,在抑制 2.型糖尿病方面具有重要应用。通过与氨基酸β-丙氨酸和2个-氨基苯甲酸进行缩合反应,用于制备含三齿席夫碱羧酸盐的配体。它还参与了咪唑导向的醛亚胺烯丙基化研究。

咪唑-2-甲醛物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
296.5±23.0 °C at 760 mmHg

[ 熔点 ]:
209 °C (dec.)(lit.)

[ 分子式 ]:
C₄H₄N₂O

[ 分子量 ]:
96.09

[ 闪点 ]:
137.5±29.0 °C

[ 精确质量 ]:
96.032364

[ PSA ]:
45.75000

[ LogP ]:
-0.33

[ 外观性状 ]:
白色粉末

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.620

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
水溶性：可溶

咪唑-2-甲醛MSDS

咪唑-2-甲醛安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S36/37/39-S3

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2933290090

咪唑-2-甲醛合成路线

咪唑-2-甲醛上下游产品

咪唑-2-甲醛上游产品

咪唑-2-甲醛下游产品

咪唑-2-甲醛海关

[ 海关编码 ]: 2933290090

[ 中文概述 ]:
2933290090. 其他结构含非稠合咪唑环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

咪唑-2-甲醛文献

Investigation of a Degradant in a Biologics Formulation Buffer Containing L-Histidine.

Pharm. Res. 32 , 2625-35, (2015)

An unknown UV 280 nm absorbing peak was observed by SEC for protein stability samples formulated in L-histidine during a stress stability study. Understanding the source would enhance the confidence i...

Mixed ligand copper(II) complexes of 1,10-phenanthroline with tridentate phenolate/pyridyl/(benz)imidazolyl Schiff base ligands: covalent vs non-covalent DNA binding, DNA cleavage and cytotoxicity.

J. Inorg. Biochem. 140 , 255-68, (2014)

A series of copper(II) complexes of the types [Cu(L)(phen)](ClO4) 1-2, where HL is a tridentate ligand with two nitrogen and one oxygen donor atoms (2NO) such as 2-(2-(1H-benzimidazol-2-yl)ethyliminom...

Helical-chain copper(II) complexes and a cyclic tetranuclear copper(II) complex with single syn-anti carboxylate bridges and ferromagnetic exchange interactions.

Inorg. Chem. 39(13) , 2882-90, (2000)

Tridentate Schiff-base carboxylate-containing ligands, derived from the condensation of 2-imidazolecarboxaldehyde with the amino acids beta-alanine (H2L1) and 2-aminobenzoic acid (H2L5) and the conden...

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