1-Propanone,1-(4-methoxyphenyl)-3-(1-piperidinyl)-, hydrochloride (1:1)

名称

[ CAS 号 ]:
1026-88-6

[ 英文名 ]:
1-Propanone,1-(4-methoxyphenyl)-3-(1-piperidinyl)-, hydrochloride (1:1)

[英文别名 ]:

1-(4-Methoxyphenyl)-3-Phenylpyrazolin
N-<2-(4-methoxybenzoyl)ethyl>piperidinium chloride
1-(4-Methoxyphenyl)-3-phenyl-2-pyrazoline

物理化学性质

[ 沸点 ]:
385ºC at 760mmHg

[ 分子式 ]:
C₁₅H₂₂ClNO₂

[ 分子量 ]:
283.79400

[ 闪点 ]:
186.6ºC

[ 精确质量 ]:
283.13400

[ PSA ]:
29.54000

[ LogP ]:
3.49380

[ 蒸汽压 ]:
3.94E-06mmHg at 25°C

[ 折射率 ]:
1.526

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UH4375000

CHEMICAL NAME :: Propiophenone, 4'-methoxy-3-piperidino-, hydrochloride

CAS REGISTRY NUMBER :: 1026-88-6

LAST UPDATED :: 199107

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C15-H21-N-O2.Cl-H

MOLECULAR WEIGHT :: 283.83

WISWESSER LINE NOTATION :: T6NTJ A2VR DO1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 137 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 12,994,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 170 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 5,559,1955

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 48 mg/kg

TOXIC EFFECTS :: Behavioral - ataxia Behavioral - muscle contraction or spasticity Behavioral - irritability

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 115,419,1955

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