GDP

GDP用途

Guanosine 5′-diphosphate (GDP) is the diphosphate nucleoside of the purine guanine. GDP and GTP are involved in and may be used to study cell signaling via G-coupled protein receptors (GCPR) and guanine nucleotide exchange factors (GEF) and a variety of GTPases.

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GDP名称

[ CAS 号 ]:
103192-39-8

[ 中文名 ]:
GDP

[ 英文名 ]:
GUANOSINE 5'-DIPHOSPHATE TRIS SALT

[英文别名 ]:

GDP物理化学性质

[ 分子式 ]:
C₁₄H₂₆N₆O₁₄P₂

[ 分子量 ]:
564.33600

[ 精确质量 ]:
564.09800

[ PSA ]:
359.89000

[ 外观性状 ]:
固体

[ 储存条件 ]:
20°C

GDPMSDS

详细MSDS(安全技术说明书)

GDP安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

GDP文献

Coronin 1A promotes a cytoskeletal-based feedback loop that facilitates Rac1 translocation and activation.

EMBO J. 30 , 3913-3927, (2011)

The activation of the Rac1 GTPase during cell signalling entails its translocation from the cytosol to membranes, release from sequestering Rho GDP dissociation inhibitors (RhoGDI), and GDP/GTP exchan...

RIC8 is a guanine-nucleotide exchange factor for Galpha subunits that regulates growth and development in Neurospora crassa.

Genetics 189 , 165-176, (2011)

Heterotrimeric (αβγ) G proteins are crucial components of eukaryotic signal transduction pathways. G-protein-coupled receptors (GPCRs) act as guanine nucleotide exchange factors (GEFs) for Gα subunits...

Insights into the molecular activation mechanism of the RhoA-specific guanine nucleotide exchange factor, PDZRhoGEF.

J. Biol. Chem. 286 , 35163-35175, (2011)

PDZRhoGEF (PRG) belongs to a small family of RhoA-specific nucleotide exchange factors that mediates signaling through select G-protein-coupled receptors via Gα(12/13) and activates RhoA by catalyzing...

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GDP