3-(2,5-dimethylphenyl)-2-methylquinazolin-4-one

名称

[ CAS 号 ]:
10367-31-4

[ 英文名 ]:
3-(2,5-dimethylphenyl)-2-methylquinazolin-4-one

[英文别名 ]:

Ro 326

物理化学性质

[ 密度 ]:
1.14g/cm3

[ 沸点 ]:
433.2ºC at 760 mmHg

[ 分子式 ]:
C₁₇H₁₆N₂O

[ 分子量 ]:
264.32200

[ 闪点 ]:
215.8ºC

[ 精确质量 ]:
264.12600

[ PSA ]:
34.89000

[ LogP ]:
3.31090

[ 蒸汽压 ]:
1.04E-07mmHg at 25°C

[ 折射率 ]:
1.614

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VA4146600

CHEMICAL NAME :: 4(3H)-Quinazolinone, 2-methyl-3-(2,5-xylyl)-

CAS REGISTRY NUMBER :: 10367-31-4

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C17-H16-N2-O

MOLECULAR WEIGHT :: 264.35

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1200 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 22,129,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 710 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 17,616,1962

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安全信息

[ 海关编码 ]:
2933990090

海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%