4-(4-氯-2-甲基苯氧基)丁酸乙酯
4-(4-氯-2-甲基苯氧基)丁酸乙酯名称
[ CAS 号 ]:
10443-70-6
[ 中文名 ]:
2甲4氯丁酸乙酯
[ 英文名 ]:
MCPB-ETHYL ESTER
[中文别名 ]:
[英文别名 ]:
- ethyl 4-(4-chloro-o-tolyloxy)butyrate
- Ethyl 4-(2-methyl-4-chlorophenoxy)butylate
- MCPB ethyl ester
- MCPB ethyl
- Ethyl 4-(4-chloro-2-methylphenoxy)butanoate
- ethyl 4-(4-chloro-2-methylphenoxy)butanoate
- MCPBE
4-(4-氯-2-甲基苯氧基)丁酸乙酯物理化学性质
[ 密度 ]:
1.127g/cm3
[ 沸点 ]:
355ºC at 760mmHg
[ 熔点 ]:
-0.9°C
[ 分子式 ]:
C13H17ClO3
[ 分子量 ]:
256.72500
[ 闪点 ]:
137.4ºC
[ 精确质量 ]:
256.08700
[ PSA ]:
35.53000
[ LogP ]:
3.37050
[ 外观性状 ]:
液体;Colorless to Light yellow to Light orange clear liquid
[ 蒸汽压 ]:
3.21E-05mmHg at 25°C
[ 折射率 ]:
1.505
[ 储存条件 ]:
0-10°C
4-(4-氯-2-甲基苯氧基)丁酸乙酯毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EK7745000
- CHEMICAL NAME :
- Butanoic acid, 4-(4-chloro-2-methylphenoxy)-, ethyl ester
- CAS REGISTRY NUMBER :
- 10443-70-6
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 14
- MOLECULAR FORMULA :
- C13-H17-Cl-O3
- MOLECULAR WEIGHT :
- 256.75
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1420 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S39,1992
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3000 mg/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S39,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S39,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 870 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S39,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3910 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S39,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1160 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S39,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 525 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S39,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3110 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S39,1992 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 31200 mg/kg/13W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Endocrine - changes in spleen weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S39,1992
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 131 gm/kg/2Y-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
- REFERENCE :
- NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S39,1992
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 750 mg/kg/6W-I
- TOXIC EFFECTS :
- Behavioral - tremor Gastrointestinal - hypermotility, diarrhea Liver - other changes
- REFERENCE :
- AMBNAS Acta Medica et Biologica (Niigata). (Niigata Univ. School of Medicine, 1 Asahi-machi-dori, Niigata 951, Japan) V.1- 1953- Volume(issue)/page/year: 38,97,1990
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1500 mg/kg/12W-I
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- AMBNAS Acta Medica et Biologica (Niigata). (Niigata Univ. School of Medicine, 1 Asahi-machi-dori, Niigata 951, Japan) V.1- 1953- Volume(issue)/page/year: 38,97,1990
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 5475 mg/kg/2Y-C
- TOXIC EFFECTS :
- Liver - hepatitis (hepatocellular necrosis), diffuse Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- REFERENCE :
- NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S39,1992 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2500 mg/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 17,S39,1992
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4-(4-氯-2-甲基苯氧基)丁酸乙酯安全信息
[ 危害码 (欧洲) ]:
Xn
[ 危险品运输编码 ]:
3082
[ RTECS号 ]:
EK7745000
[ 包装等级 ]:
III
推荐生产厂家/供应商：
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥3771.0/1g
￥680.0/100mg
￥需询单/1g
￥需询单/1g
联系人：阿拉丁李高志
产品详情：4-(4-氯-2-甲基苯氧基)丁酸乙酯
公司名：上海创赛科技有限公司
区域：上海市嘉定区
价格：
￥747.0/100mg
联系人：夏言
产品详情：[Perfemiker]4-(4-氯-2-甲基苯氧基)丁酸乙酯,≥98%(GC)
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相关化合物
[4-(4-氯-2-甲基苯氧基)丁酸乙酯]化源网提供4-(4-氯-2-甲基苯氧基)丁酸乙酯CAS号10443-70-6，4-(4-氯-2-甲基苯氧基)丁酸乙酯MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询4-(4-氯-2-甲基苯氧基)丁酸乙酯上化源网，专业又轻松。>>电脑版：4-(4-氯-2-甲基苯氧基)丁酸乙酯
标题：10443-70-6_4-(4-氯-2-甲基苯氧基)丁酸乙酯CAS号:10443-70-6_4-(4-氯-2-甲基苯氧基)丁酸乙酯【结构式 性质 英文】 - 化源网 地址：https://m.chemsrc.com/mip/cas/10443-70-6_179030.html