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GppCp(GMPPCP)

GppCp(GMPPCP)用途

5′-鸟苷基亚甲基二磷酸钠是GTP类似物,是蛋白质合成中GTP反应的特异性竞争性抑制剂[1]。

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GppCp(GMPPCP)名称

[ CAS 号 ]:
10470-57-2

[ 英文名 ]:
GppCp(GMPPCP)

[英文别名 ]:

GMPPCP
GppCp

GppCp(GMPPCP)生物活性

[ 描述 ]:

5′-鸟苷基亚甲基二磷酸钠是GTP类似物,是蛋白质合成中GTP反应的特异性竞争性抑制剂[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Hershey JW, et.al. A competitive inhibitor of the GTP reaction in protein synthesis. J Mol Biol. 1966 Jun;18(1):68-76.

GppCp(GMPPCP)物理化学性质

[ 分子式 ]:
C₁₁H₁₅N₅Na₃O₁₃P₃

[ 分子量 ]:
587.15

[ 精确质量 ]:
544.00100

[ PSA ]:
320.29000

[ 储存条件 ]:
-20°C，干燥

GppCp(GMPPCP)MSDS

详细MSDS(安全技术说明书)

GppCp(GMPPCP)安全信息

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

GppCp(GMPPCP)文献

Polarized endosome dynamics by spindle asymmetry during asymmetric cell division.

Nature 528 , 280-5, (2015)

During asymmetric division, fate determinants at the cell cortex segregate unequally into the two daughter cells. It has recently been shown that Sara (Smad anchor for receptor activation) signalling ...

Dynamic and thermodynamic response of the Ras protein Cdc42Hs upon association with the effector domain of PAK3.

J. Mol. Biol. 426(21) , 3520-38, (2014)

Human cell division cycle protein 42 (Cdc42Hs) is a small, Rho-type guanosine triphosphatase involved in multiple cellular processes through its interactions with downstream effectors. The binding dom...

Regulation of human tissue transglutaminase function by magnesium-nucleotide complexes. Identification of distinct binding sites for Mg-GTP and Mg-ATP.

J. Biol. Chem. 273 , 1776-1781, (1998)

Tissue transglutaminase (tTG) catalyzes a Ca(2+)-dependent transglutaminase (TGase) activity that stabilizes tissues and a GTP hydrolysis activity that regulates cell receptor signaling. The purpose o...

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