N,N-二甲基二丙烯三胺
N,N-二甲基二丙烯三胺名称
[ CAS 号 ]:
10563-29-8
[ 中文名 ]:
N,N-二甲基亚二丙基三胺
[ 英文名 ]:
N,N-Dimethyldipropylenetriamine
[中文别名 ]:
[英文别名 ]:
- N'-(3-Aminopropyl)-N,N-dimethyl-1,3-propanediamine
- EINECS 234-148-4
- dimethyldipropylene-triamine
- N'-[3-(dimethylamino)propyl]propane-1,3-diamine
- N'-(3-Aminopropyl)-N,N-dimethylpropane-1,3-diamine
- MFCD00082192
N,N-二甲基二丙烯三胺物理化学性质
[ 密度 ]:
0.883
[ 沸点 ]:
231 ºC
[ 分子式 ]:
C8H21N3
[ 分子量 ]:
159.272
[ 闪点 ]:
94 ºC
[ 精确质量 ]:
159.173553
[ PSA ]:
41.29000
[ LogP ]:
-0.41
[ 外观性状 ]:
无色液体
[ 蒸汽压 ]:
0.1±0.5 mmHg at 25°C
[ 折射率 ]:
1.466
[ 储存条件 ]:
室温
N,N-二甲基二丙烯三胺MSDS
N,N-二甲基二丙烯三胺毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TX7000000
- CHEMICAL NAME :
- 1,3-Propanediamine, N'-(3-aminopropyl)-N,N-dimethyl-
- CAS REGISTRY NUMBER :
- 10563-29-8
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C8-H21-N3
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 1432 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - excitement
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 28(11),50,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 72 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - excitement
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 28(11),50,1984 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 72 mg/kg/3D-I
- TOXIC EFFECTS :
- Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 28(11),50,1984
N,N-二甲基二丙烯三胺安全信息
[ 符号 ]:
GHS05, GHS07, GHS09
[ 信号词 ]:
Danger
[ 危害声明 ]:
H302 + H312-H314-H317-H411
[ 警示性声明 ]:
P260-P280-P301 + P312 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
C
[ 风险声明 (欧洲) ]:
R21/22
[ 安全声明 (欧洲) ]:
23-26-36/37/39-45
[ 危险品运输编码 ]:
UN 2735 8
[ WGK德国 ]:
1
[ RTECS号 ]:
TX7000000
[ 包装等级 ]:
III
[ 危险类别 ]:
8.0
[ 海关编码 ]:
2921290000
N,N-二甲基二丙烯三胺合成路线
N,N-二甲基二丙烯三胺海关
[ 海关编码 ]: 2921290000
[ 中文概述 ]:
2921290000. 其他无环多胺及其衍生物及它们的盐. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
N,N-二甲基二丙烯三胺文献
Biomaterials 34(18) , 4520-31, (2013)
The low toxicity and efficient gene delivery of polymeric vectors remain the major barrier to the clinical application of non-viral gene therapy. Here, we present a poly-D, L-succinimide (PSI)-based b...
[Toxicity of several aliphatic amines].Gig. Tr. Prof. Zabol. (11) , 50-3, (1984)
Efficacy of gemcitabine conjugated and miRNA-205 complexed micelles for treatment of advanced pancreatic cancer.
Biomaterials 35(25) , 7077-87, (2014)
Clinical effectiveness of gemcitabine in pancreatic cancer is hindered due to its rapid plasma metabolism and development of chemo-resistance. We have previously delineated the significant role of miR...
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