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伪赤藓霉素A烯醇醚

伪赤藓霉素A烯醇醚用途

Pseudoerythromycin A enol ether (LY267108) 是红霉素的降解产物。Pseudoerythromycin A enol ether 无明显抑菌活性。

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伪赤藓霉素A烯醇醚名称

[ CAS 号 ]:
105882-69-7

[ 中文名 ]:
伪赤藓霉素A烯醇醚

[ 英文名 ]:
Pseudoerythromycin A enol ether

[英文别名 ]:

Pseudoerythromycin A enol ether

伪赤藓霉素A烯醇醚生物活性

[ 描述 ]:

Pseudoerythromycin A enol ether (LY267108) 是红霉素的降解产物。Pseudoerythromycin A enol ether 无明显抑菌活性。

[ 相关类别 ]:

研究领域 >> 其他

[参考文献]

[1]. Pendela M, et al. Combined use of liquid chromatography with mass spectrometry and nuclear magnetic resonance for the identification of degradation compounds in an erythromycin formulation. Anal Bioanal Chem. 2012;402(2):781-790.

[2]. Greenwood B, et al. Effects of LY267108, an erythromycin analogue derivative, on lower esophageal sphincter function in the cat. Gastroenterology. 1994;106(3):624-628.

伪赤藓霉素A烯醇醚物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
810.7±65.0 °C at 760 mmHg

[ 分子式 ]:
C₃₇H₆₅NO₁₂

[ 分子量 ]:
715.911

[ 闪点 ]:
444.1±34.3 °C

[ 精确质量 ]:
715.450684

[ PSA ]:
165.84000

[ LogP ]:
3.01

[ 蒸汽压 ]:
0.0±6.6 mmHg at 25°C

[ 折射率 ]:
1.542

[ 储存条件 ]:
−20°C

伪赤藓霉素A烯醇醚安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

伪赤藓霉素A烯醇醚上下游产品

伪赤藓霉素A烯醇醚上游产品

伪赤藓霉素A烯醇醚下游产品

伪赤藓霉素A烯醇醚文献

Effects of LY267108, an erythromycin analogue derivative, on lower esophageal sphincter function in the cat.

Gastroenterology 106(3) , 624-8, (1994)

Erythromycin (EM-A) and some of its analogues stimulate gastrointestinal smooth muscle contractions. Because gastroesophageal reflux disease (GERD) in humans is in part caused by a reduction in lower ...

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