2,6-二甲基吡啶

2,6-二甲基吡啶用途

【用途一】
用作有机合成原料
【用途二】
该品在有机合成中用途广泛。医药工业中可用于生产抗动脉粥样硬化药血脉宁。还可用于生产对蛔虫、布氏姜片虫、鞭虫、蛲虫等有效的广谱驱虫药驱蛲净。以及可的松乙酸酯、氢化可的松、烟酸、芦别林等等。2,6-二甲基吡啶还可用作农药、染料、印染助剂、树脂、橡胶硫化促进剂、热油安定剂的中间体。本品经氧化可得到二甲基吡啶酸，用作过氧化氢和过乙酸的稳定剂，还能合成山梗碱。该品也可用作溶剂。
【用途三】
用于合成各种治疗高血压病的药及急救药，另外还用作杀虫剂及助染剂。

点击显示

2,6-二甲基吡啶名称

[ CAS 号 ]:
108-48-5

[ 中文名 ]:
2,6-二甲基吡啶

[ 英文名 ]:
2,6-lutidine

[中文别名 ]:

[英文别名 ]:

Lutidine
2,6-Dimethylpyridine
EINECS 203-587-3
Pyridine, 2,6-dimethyl-
2,6-Lutidine
MFCD00006345

2,6-二甲基吡啶物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
144.0±0.0 °C at 760 mmHg

[ 熔点 ]:
-6 °C

[ 分子式 ]:
C₇H₉N

[ 分子量 ]:
107.153

[ 闪点 ]:
33.3±0.0 °C

[ 精确质量 ]:
107.073502

[ PSA ]:
12.89000

[ LogP ]:
1.65

[ 外观性状 ]:
黄色

[ 蒸汽压 ]:
6.5±0.2 mmHg at 25°C

[ 折射率 ]:
1.502

[ 储存条件 ]:
库房通风低温干燥,与氧化剂、酸类分开存放

[ 稳定性 ]:
Stable. Flammable. Incompatible with strong oxidizing agents, acid chlorides, acids, chloroformates. Protect from moisture.

[ 水溶解性 ]:
40 g/100 mL (20 ºC)

2,6-二甲基吡啶MSDS

详细MSDS(安全技术说明书)

2,6-二甲基吡啶毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OK9700000

CHEMICAL NAME :: 2,6-Lutidine

CAS REGISTRY NUMBER :: 108-48-5

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C7-H9-N

MOLECULAR WEIGHT :: 107.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7500 ppm/1H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TEST SYSTEM :: Yeast - Saccharomyces cerevisiae

DOSE/DURATION :: 5000 ppm

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 163,23,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2110 No. of Facilities: 34 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 5202 (estimated) No. of Female Employees: 390 (estimated)

点击显示

2,6-二甲基吡啶安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H226-H302-H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R10;R20/21/22

[ 安全声明 (欧洲) ]:
S26-S36/37-S16-S36

[ 危险品运输编码 ]:
UN 1993 3/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
OK9700000

[ 包装等级 ]:
III

[ 危险类别 ]:
3

[ 海关编码 ]:
29333999

2,6-二甲基吡啶合成路线

详细合成路线

2,6-二甲基吡啶上下游产品

2,6-二甲基吡啶上游产品

2,6-二甲基吡啶下游产品

2,6-二甲基吡啶制备

1、通过从煤炼焦副产物中回收β-甲基吡啶馏分中分离得到。

通常含有3-和4-甲基吡啶，难用分馏的方法分离。一般利用与水组成的共沸混合物（共沸点95.5~96℃），进行精馏以达分离的目的。其他尚有与尿素形成加成物进行分离的方法；生成盐酸盐进行分离的方法；用硫酸亚镍、硫氰化铵混合溶液处理，使3-和4-甲基吡啶形成加成物而除去的方法等。

2、乙酰乙酸乙酯法乙酰乙酸乙酯经环合、氧化、水解、碱解制得。

3、其纯化方法见文献。

点击显示

2,6-二甲基吡啶海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2,6-二甲基吡啶文献

High-throughput chemical modification of oligonucleotides for systematic structure-activity relationship evaluation.

Bioconjug. Chem. 25(12) , 2222-32, (2014)

Chemical modification of siRNA is achieved in a high-throughput manner (96-well plate format) by copper catalyzed azide-alkyne cycloadditions. This transformation can be performed in one synthetic ope...

Ambient preparation and reactions of gas phase silver cluster cations and anions.

Phys. Chem. Chem. Phys. 17 , 18364-73, (2015)

Electrospray ionization of metal salt solutions followed by ambient heating transforms the resulting salt clusters into new species, primarily naked ionic metal clusters. The experiment is done by pas...

Sugar composition of the pectic polysaccharides of charophytes, the closest algal relatives of land-plants: presence of 3-O-methyl-D-galactose residues.

Ann. Bot. 116 , 225-36, (2015)

During evolution, plants have acquired and/or lost diverse sugar residues as cell-wall constituents. Of particular interest are primordial cell-wall features that existed, and in some cases abruptly c...

更多文献

2,6-二甲基吡啶

2,6-二甲基吡啶用途

2,6-二甲基吡啶名称

2,6-二甲基吡啶物理化学性质

2,6-二甲基吡啶MSDS

详细MSDS(安全技术说明书)

2,6-二甲基吡啶毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

2,6-二甲基吡啶安全信息

2,6-二甲基吡啶合成路线

详细合成路线

2,6-二甲基吡啶上下游产品

2,6-二甲基吡啶上游产品

2,6-二甲基吡啶下游产品

2,6-二甲基吡啶制备

2,6-二甲基吡啶海关

2,6-二甲基吡啶文献

相关化工产品/化学物质：

推荐生产厂家/供应商：

相关化合物