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N-Fmoc-N'-三苯甲基-L-组氨酸

N-Fmoc-N'-三苯甲基-L-组氨酸用途

Fmoc-His(Trt)-OH具有三苯基(Trt)基团以保护His的侧链。Fmoc-His(Trt)-OH具有Fmoc基团以保护-αNH2。Fmoc-His(Trt)-OH可用于肽的固相合成,提供防止外消旋和副产物形成的保护[1]。

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N-Fmoc-N'-三苯甲基-L-组氨酸名称

[ CAS 号 ]:
109425-51-6

[ 中文名 ]:
N-Fmoc-N'-三苯甲基-L-组氨酸

[ 英文名 ]:
Fmoc-His(Trt)-OH

[中文别名 ]:

[英文别名 ]:

MFCD00043332
N-Fmoc-N'-Trityl-L-Histidine
N-alpha-FMOC-N-Trityl-L-histidine
EINECS 439-640-4
Nα-Fmoc-N(im)-trityl-L-histidine
Na-Fmoc-Nim-trityl-L-histidine
Fmoc-His(Trt)-OH
Nα-Fmoc-τ-trityl-L-histidine

N-Fmoc-N'-三苯甲基-L-组氨酸生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Yi Y, et, al. Suppression of Simultaneous Fmoc-His(Trt)-OH Racemization and Nα-DIC-Endcapping in Solid-Phase Peptide Synthesis through Design of Experiments and Its Implication for an Amino Acid Activation Strategy in Peptide Synthesis. Org. Process Res. Dev. 2022 Jun 27.

N-Fmoc-N'-三苯甲基-L-组氨酸物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
811.7±65.0 °C at 760 mmHg

[ 熔点 ]:
150-155 °C(lit.)

[ 分子式 ]:
C₄₀H₃₃N₃O₄

[ 分子量 ]:
619.708

[ 闪点 ]:
444.7±34.3 °C

[ 精确质量 ]:
619.247131

[ PSA ]:
93.45000

[ LogP ]:
8.03

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.0±3.1 mmHg at 25°C

[ 折射率 ]:
1.657

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
可溶于：二甲基甲酰胺

N-Fmoc-N'-三苯甲基-L-组氨酸MSDS

N-Fmoc-N'-三苯甲基-L-组氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

N-Fmoc-N'-三苯甲基-L-组氨酸合成路线

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N-Fmoc-N'-三苯甲基-L-组氨酸文献

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