2-丁炔-1,4-二醇
2-丁炔-1,4-二醇用途
初级镀镍光亮剂
【用途二】
用于生产丁烯二醇、丁二醇、γ-丁内酯等系列化工产品
【用途三】
用作有机合成中间体及仪表电镀用的材料
【用途四】
丁炔二醇可以制造丁烯二醇、丁二醇、正丁醇、二氢呋喃、四氢呋喃、γ-丁内酯、吡咯烷酮等一系列重要的有机产品，进一步可以制造合成塑料、合成纤维（尼龙-4）、人造革、医药、农药、溶剂（N-甲基吡咯烷酮）和防腐剂。丁炔二醇本身是良好的溶剂，在电镀工业中作光亮剂。
【用途五】
丁二烯合成的中间体，腐蚀抑制剂，电镀光亮剂，聚合催化剂，脱叶剂，氯烃稳定剂。
2-丁炔-1,4-二醇名称
[ CAS 号 ]:
110-65-6
[ 中文名 ]:
丁炔二醇
[ 英文名 ]:
2-Butine-1,4-diol
[中文别名 ]:
[英文别名 ]:
- 1,4-Butynediol
- 1,4-dihydroxy-2-butyne
- But-2-in-1,4-diol
- EINECS 203-788-6
- 2-Butyne-1,4-diol
- But-2-yne-1,4-diol
- 2-Butine-1,4-diol
- 1,2-Dihydroxydimethylacetylene
- MFCD01075157
- BOZ
2-丁炔-1,4-二醇物理化学性质
[ 密度 ]:
1.2±0.1 g/cm3
[ 沸点 ]:
238.0±8.0 °C at 760 mmHg
[ 熔点 ]:
54 °C
[ 分子式 ]:
C4H6O2
[ 分子量 ]:
86.089
[ 闪点 ]:
152.2±0.0 °C
[ 精确质量 ]:
86.036781
[ PSA ]:
40.46000
[ LogP ]:
-1.10
[ 外观性状 ]:
白色至淡棕色固体或褐色-黄色水状的溶液
[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C
[ 折射率 ]:
1.506
[ 储存条件 ]:
库房通风低温干燥,与氧化剂、酸类分开存放
[ 稳定性 ]:
Stable. Highly flammable solid. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides, strong acids, strong bases.
[ 水溶解性 ]:
3740 g/L (20 ºC)
2-丁炔-1,4-二醇MSDS
2-丁炔-1,4-二醇毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ES0525000
- CHEMICAL NAME :
- 2-Butyne-1,4-diol
- CAS REGISTRY NUMBER :
- 110-65-6
- BEILSTEIN REFERENCE NO. :
- 1071237
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 19
- MOLECULAR FORMULA :
- C4-H6-O2
- MOLECULAR WEIGHT :
- 86.10
- WISWESSER LINE NOTATION :
- Q2UU2Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 105 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory stimulation Blood - other changes
- REFERENCE :
- HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 33(1-3),41,1968
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 150 mg/m3/2H
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Blood - hemorrhage
- REFERENCE :
- TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 7,13,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 52435 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 26,597,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 105 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory stimulation Blood - other changes
- REFERENCE :
- HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 33(1-3),41,1968
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 150 mg/m3/2H
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Blood - hemorrhage
- REFERENCE :
- TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 7,13,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory stimulation Blood - other changes
- REFERENCE :
- HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 33(1-3),41,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 130 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory stimulation Blood - other changes
- REFERENCE :
- HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 33(1-3),41,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - wild bird species
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1400 mg/kg/28D-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Blood - changes in leukocyte (WBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases
- REFERENCE :
- JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 12,117,1992
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 364 mg/kg/26W-I
- TOXIC EFFECTS :
- Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Metabolism (Intermediary) - other carbohydrates
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 33(1),37,1968
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1400 mg/kg/14D-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 43,87,1989
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8 mg/m3/4H/26W-I
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Vascular - BP lowering not characterized in autonomic section Liver - liver function tests impaired
- REFERENCE :
- TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 7,13,1965
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 90 mg/m3/2H/30D-I
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes Blood - hemorrhage Related to Chronic Data - death
- REFERENCE :
- TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 7,13,1965 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 1 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2524 No. of Facilities: 307 (estimated) No. of Industries: 7 No. of Occupations: 11 No. of Employees: 2173 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2524 No. of Facilities: 1139 (estimated) No. of Industries: 21 No. of Occupations: 20 No. of Employees: 16527 (estimated) No. of Female Employees: 4755 (estimated)
2-丁炔-1,4-二醇安全信息
[ 危害码 (欧洲) ]:
T:Toxic
[ 风险声明 (欧洲) ]:
R21;R23/25;R34;R43;R48/22
[ 安全声明 (欧洲) ]:
S25-S26-S36/37/39-S45-S46
[ 危险品运输编码 ]:
UN 2716 6.1/PG 3
[ WGK德国 ]:
2
[ RTECS号 ]:
ES0525000
[ 包装等级 ]:
III
[ 危险类别 ]:
6.1
[ 海关编码 ]:
2905399090
2-丁炔-1,4-二醇上下游产品
2-丁炔-1,4-二醇上游产品
2-丁炔-1,4-二醇下游产品
2-丁炔-1,4-二醇制备
1.采用乙炔甲醛合成法 含80%-90%的乙炔经压缩至0.4-0.5MPa的压力，预热至70-80℃，送至反应器，以丁炔酮为催化剂，和甲醛于110-112℃反应，得粗品。反应产物经浓缩、精制得成品，同时副产丙炔醇。
2.多聚甲醛常压溶剂法：以多聚甲醛为原料，以环乙酮等作溶剂，在催化剂乙炔铜存在下，向反应器中通入乙炔，保持温度115-120℃，待甲醛完全后转化后停止通乙炔，滤出催化剂，反应液经浓缩再结晶，可得结晶状丁炔二醇。
2-丁炔-1,4-二醇海关
[ 海关编码 ]: 2905399090
[ 中文概述 ]:
2905399090 其他二元醇。监管条件:AB(入境货物通关单,出境货物通关单)。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 包装
[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单
[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验
[ Summary ]:
2905399090 other diols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%
相关化工产品/化学物质：
推荐生产厂家/供应商：
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥128.0/500g
联系人：刘佳
产品详情：2-丁炔-1,4-二醇
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥98.0/5g
￥需询单/1g
￥需询单/1g
￥需询单/1g
联系人：阿拉丁李高志
产品详情：1,4-丁炔二醇
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相关化合物
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