α-肌动蛋白

α-肌动蛋白用途

α-Actinin exists as a rod-shaped antiparallel dimer with two elongated subunits. The domain region contains an N-terminal actin-binding domain with tandem calponin homology domains, a central tandem 3-helix motifs, and EF-hand motifs at C-terminus. It belongs to the spectrin superfamily and is localized in actin structures.

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α-肌动蛋白名称

[ CAS 号 ]:
11003-00-2

[ 中文名 ]:
α-肌动蛋白

[ 英文名 ]:
ALPHA-ACTININ

[英文别名 ]:

2-Quinolineethanol, α-(3-aminophenyl)-
1-(3-Aminophenyl)-2-(2-quinolinyl)ethanol

α-肌动蛋白物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
461.6±35.0 °C at 760 mmHg

[ 分子式 ]:
C₁₇H₁₆N₂O

[ 分子量 ]:
264.322

[ 闪点 ]:
233.0±25.9 °C

[ 精确质量 ]:
264.126251

[ LogP ]:
1.61

[ 外观性状 ]:
白色悬浊液

[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C

[ 折射率 ]:
1.706

[ 储存条件 ]:
2-8°C

α-肌动蛋白安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ 危险品运输编码 ]:
NONH for all modes of transport

α-肌动蛋白文献

Androgen therapy reverses injuries caused by ethanol consumption in the prostate: testosterone as a possible target to ethanol-related disorders.

Life Sci. 120 , 22-30, (2015)

Chronic ethanol consumption leads to reproductive damages, since it can act directly in the tissues or indirectly, causing a hormonal imbalance. Prostate is a hormone-dependent gland and, consequently...

Modulation of stretch-induced myocyte remodeling and gene expression by nitric oxide: a novel role for lipoma preferred partner in myofibrillogenesis.

Am. J. Physiol. Heart Circ. Physiol. 304(10) , H1302-13, (2013)

Prolonged hemodynamic load as a result of hypertension eventually leads to maladaptive cardiac adaptation and heart failure. The signaling pathways that underlie these changes are still poorly underst...

Interference with the contractile machinery of the fibroblastic chondrocyte cytoskeleton induces re-expression of the cartilage phenotype through involvement of PI3K, PKC and MAPKs.

Exp. Cell Res. 320(2) , 175-87, (2014)

Chondrocytes rapidly lose their phenotypic expression of collagen II and aggrecan when grown on 2D substrates. It has generally been observed that a fibroblastic morphology with strong actin-myosin co...

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