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pTH-Related Protein (1-34) amide (human, mouse, rat) trifluoroacetate salt

用途

pTH-Related Protein (1-34) amide (human, mouse, rat) 是 PTHrP 的 N 末端片段。pTH-Related Protein (1-34) amide (human, mouse, rat) 诱导高钙血症,可用于恶性肿瘤体液高钙血症的研究。
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名称

[ CAS 号 ]:
112955-31-4

[ 英文名 ]:
pTH-Related Protein (1-34) amide (human, mouse, rat) trifluoroacetate salt

生物活性

[ 描述 ]:

pTH-Related Protein (1-34) amide (human, mouse, rat) 是 PTHrP 的 N 末端片段。pTH-Related Protein (1-34) amide (human, mouse, rat) 诱导高钙血症,可用于恶性肿瘤体液高钙血症的研究。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他
研究领域 >> 代谢疾病

[参考文献]

[1]. Horiuchi N, et al. A 7-34 analog of the parathyroid hormone-related protein has potent antagonist and partial agonist activity in vivo. Bone Miner. 1991 Mar;12(3):181-8.  

[2]. McFarlane DR, et al. FTIR spectroscopy study of PTHrP(1-34) involved in humoral hypercalcaemia of malignancy. Biochim Biophys Acta. 1993 Mar 5;1162(1-2):187-94.  

物理化学性质

[ 分子式 ]:
C180H288N58O47

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

文献

Parathyroid hormone-related protein of malignancy: active synthetic fragments.

Science 238 , 1568, (1967)

Peptides corresponding to the amino-terminal region of the parathyroid hormone-related protein (PTHrP) of humoral hypercalcemia of malignancy were synthesized. A 34-amino acid peptide, PTHrP(1-34), wa...

Parathyroid hormone-related peptide stimulates proliferation of highly tumorigenic human SV40-immortalized breast epithelial cells.

J. Bone Miner Res. 15 , 2129-2139, (2000)

Parathyroid hormone-related protein (PTHrP) is the main mediator of humoral hypercalcemia of malignancy (HHM) and it is produced by many tumors, including breast cancers. Breast epithelial cells as we...

Etomidate is associated with mortality and adrenal insufficiency in sepsis: a meta-analysis*.

Science 238 , 1566, (1987)

To evaluate the effects of single-dose etomidate on the adrenal axis and mortality in patients with severe sepsis and septic shock.A systematic review of randomized controlled trials and observational...


更多文献

推荐生产厂家/供应商：

公司名：吉尔生化（上海）有限公司

区域：上海市闵行区

价格：
$需询单/1g

联系人：杨经理

产品详情：Hypercalcemia Malignancy Factor (1-34)

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