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4-(二甲氨基)芪

4-(二甲氨基)芪名称

[ CAS 号 ]:
1145-73-9

[ 中文名 ]:
4-(二甲氨基)芪

[ 英文名 ]:
N,N-Dimethyl-p-styrylaniline

[中文别名 ]:

4-(二甲基氨基)芪

[英文别名 ]:

N,N-dimethyl-4-[(E)-2-phenylethenyl]aniline
4-(N,N-dimethylamino)-stilbene
4-(Dimethylamino)stibene
N,N-Dimethylstilben-4-amine
n,n-dimethyl-4-aminostilbene
N,N-dimethyl-N-[4-(2-phenylvinyl)phenyl]amine
N,N-Dimethyl-p-styrylaniline
dimethyl-stilben-4-yl-amine
Benzenamine, N,N-dimethyl-4-[(E)-2-phenylethenyl]-
Dimethylaminostilbene

4-(二甲氨基)芪物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
362.7±22.0 °C at 760 mmHg

[ 熔点 ]:
149ºC

[ 分子式 ]:
C₁₆H₁₇N

[ 分子量 ]:
223.313

[ 闪点 ]:
147.3±15.3 °C

[ 精确质量 ]:
223.136093

[ PSA ]:
3.24000

[ LogP ]:
5.34

[ 外观性状 ]:
固体;Light yellow to Brown to Dark green powder to crystaline

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.662

[ 储存条件 ]:
室温

[ 水溶解性 ]:
微溶：苯

4-(二甲氨基)芪MSDS

详细MSDS(安全技术说明书)

4-(二甲氨基)芪毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WJ3850000

CHEMICAL NAME :: 4-Stilbenamine, N,N-dimethyl-

CAS REGISTRY NUMBER :: 1145-73-9

LAST UPDATED :: 199410

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C16-H17-N

MOLECULAR WEIGHT :: 223.34

WISWESSER LINE NOTATION :: 1N1&R D1U1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 70 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 180 mg/kg/9W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Skin and Appendages - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 520 mg/kg/49W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 383 mg/kg/46W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 305 mg/kg/43W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 370 mg/kg/26W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4200 mg/kg/20W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified Liver - tumors

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Bacillus subtilis

DOSE/DURATION :: 5 gm/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 42,19,1977 *** REVIEWS *** TOXICOLOGY REVIEW ALLVAR Alimentation et la Vie. (Societe Scientifique d'Hygiene Alimentaire, 16, rue de l'Estrapade, 75005 Paris, France) V.39- 1951- Volume(issue)/page/year: 50,77,1962 TOXICOLOGY REVIEW ONCOBS Oncology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.21- 1967- Volume(issue)/page/year: 33,66,1976

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4-(二甲氨基)芪安全信息

[ RTECS号 ]:
WJ3850000