三氯乙基磷酸酯
三氯乙基磷酸酯用途
主要用于聚氨酯泡沫阻燃以及聚氯乙烯阻燃增塑等
【用途二】
本品广泛用于化纤织物、醋酸纤维素作阻燃剂，除具有自熄性外，还可改善耐水性、耐寒性及抗静电性。一般用量5～10份。
【用途三】
阻燃剂，广泛用于醋酸纤维素、硝基纤维素、乙基纤维素、聚氯乙烯、聚氨酯、聚醋酸乙烯和酚醛树脂。用作阻燃性增塑剂。还可用作金属萃取剂、润滑油和汽油添加剂，以及聚酰亚胺加工改性剂。大鼠口毒性LD50为1410mg/kg。
三氯乙基磷酸酯名称
[ CAS 号 ]:
115-96-8
[ 中文名 ]:
磷酸三(2-氯乙基)酯
[ 英文名 ]:
TCEP
[中文别名 ]:
[英文别名 ]:
- Celluflex
- MFCD00000967
- 2-Chloroethanol phosphate (3:1)
- Phosphoric Acid Tris(2-chloroethyl) Ester
- Tri(β-chloroethyl) phosphate
- fyrolcef
- Tris(2-chloroethyl) phosphate
- Phosphoric acid, tris(2-chloroethyl) ester
- Tris(β-chloroethyl) phosphate
- Niax 3CF
三氯乙基磷酸酯物理化学性质
[ 密度 ]:
1.4±0.1 g/cm3
[ 沸点 ]:
347.4±0.0 °C at 760 mmHg
[ 熔点 ]:
-51 °C
[ 分子式 ]:
C6H12Cl3O4P
[ 分子量 ]:
285.490
[ 闪点 ]:
232.2±0.0 °C
[ 精确质量 ]:
283.953888
[ PSA ]:
54.57000
[ LogP ]:
0.48
[ 外观性状 ]:
无气味的透明液体
[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C
[ 折射率 ]:
1.463
[ 储存条件 ]:
库房低温,通风,干燥
[ 稳定性 ]:
Stable. Incompatible with strong bases, strong oxidizing agents.
[ 水溶解性 ]:
7 g/L (20 ºC)
三氯乙基磷酸酯MSDS
三氯乙基磷酸酯毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KK2450000
- CAS REGISTRY NUMBER :
- 115-96-8
- BEILSTEIN REFERENCE NO. :
- 1710938
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 26
- MOLECULAR FORMULA :
- C6-H12-Cl3-O4-P
- MOLECULAR WEIGHT :
- 285.50
- WISWESSER LINE NOTATION :
- G2OPO&O2GO2G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1230 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1866 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Behavioral - somnolence (general depressed activity) Gastrointestinal - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2100 mg/kg/16D-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - changes in lung weight Kidney, Ureter, Bladder - changes in bladder weight Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 28 gm/kg/16W-I
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56 gm/kg/16W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Kidney, Ureter, Bladder - other changes Kidney, Ureter, Bladder - changes in bladder weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56 gm/kg/16W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - changes in bladder weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 45760 mg/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 182 gm/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1800 mg/kg
- SEX/DURATION :
- female 7-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - behavioral
- TYPE OF TEST :
- Micronucleus test
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 700 mg/L
- REFERENCE :
- EJCODS European Journal of Cancer and Clinical Oncology. (Pergamon Press, c/o Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591) V.17(7)- 25, 1981-89. For publisher information, see EJCAEL Volume(issue)/page/year: 18,1337,1982 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,109,1990 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,109,1990 TOXICOLOGY REVIEW CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 17,101,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M0756 No. of Facilities: 95 (estimated) No. of Industries: 5 No. of Occupations: 9 No. of Employees: 762 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M0756 No. of Facilities: 278 (estimated) No. of Industries: 6 No. of Occupations: 5 No. of Employees: 5073 (estimated) No. of Female Employees: 578 (estimated)
三氯乙基磷酸酯安全信息
[ 符号 ]:
GHS07, GHS08, GHS09
[ 信号词 ]:
Danger
[ 危害声明 ]:
H302-H351-H360F-H411
[ 警示性声明 ]:
P201-P273-P281-P308 + P313
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
Xn:Harmful
[ 风险声明 (欧洲) ]:
R22;R40;R51/53
[ 安全声明 (欧洲) ]:
S36/37-S61
[ 危险品运输编码 ]:
UN 2810 6.1/PG 3
[ WGK德国 ]:
3
[ RTECS号 ]:
KK2450000
[ 海关编码 ]:
2919900090
三氯乙基磷酸酯合成路线
三氯乙基磷酸酯上下游产品
三氯乙基磷酸酯上游产品
三氯乙基磷酸酯下游产品
三氯乙基磷酸酯制备
2、将326 kg三氯氧磷和1.0 kg偏钒酸钠投入反应釜中。充氮驱尽反应釜中的空气，在真空下通入650 kg环氧乙烷，于45～50 ℃下搅拌2～3 h。蒸出过量的环氧乙烷后加碱中和至中性，水洗，真空脱水。得成品。反应式如下：
3.将三氯氧磷和偏磷酸钠投入反应釜中。充氮驱尽空气，在真空下通入环氧乙烷，于45～50℃下搅拌2～3h。蒸出过量的环氧乙烷后加碱中和至中性，水洗，真空脱水得成品。
三氯乙基磷酸酯海关
[ 海关编码 ]: 2919900090
[ 中文概述 ]:
HS:2919900090 其他磷酸酯及其盐（包括乳磷酸盐）（包括它们的卤化，磺化，硝化和亚硝化衍生物） 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单
[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验
[ Summary ]:
2919900090 other phosphoric esters and their salts, including lactophosphates; their halogenated, sulphonated, nitrated or nitrosated derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%
三氯乙基磷酸酯文献
J. Chromatogr. A. 1401 , 33-41, (2015)
A multi-residue analytical method was developed for the determination of a range of flame retardants (FRs), including polybrominated diphenyl ethers (PBDEs), emerging halogenated FRs (EFRs) and organo...
Determination of phosphoric acid triesters in human plasma using solid-phase microextraction and gas chromatography coupled to inductively coupled plasma mass spectrometry.J. Chromatogr. A. 1103(2) , 329-36, (2006)
A simple and sensitive method for determination of phosphoric acid triesters at trace levels in human plasma sample is described. In this work, solid-phase microextraction (SPME) is employed as a samp...
Evaluation of two passive samplers for the analysis of organophosphate esters in the ambient air.Talanta 147 , 69-75, (2015)
Both polyurethane foam (PUF) and sorbent-impregnated PUF (SIP) passive air sampling (PAS) methods were deployed and compared separately for the analysis of organophosphate esters (OPEs) in outdoor atm...
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推荐生产厂家/供应商：
公司名：上海化源世纪贸易有限公司
区域：上海市普陀区
价格：
联系人：徐经理
产品详情：三(2-氯乙基)磷酸酯
公司名：吉尔生化（上海）有限公司
区域：上海市闵行区
价格：
$需询单/1g
联系人：杨经理
产品详情：TCEP
公司名：南通润丰石油化工有限公司
区域：南通市崇川区
价格：
￥需询单/1kg
￥需询单/1ton
联系人：曹经理
产品详情：三(2-氯乙基)磷酸酯
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥145.0/100g
￥565.0/500g
联系人：刘佳
产品详情：三(2-氯乙基)磷酸酯
公司名：上海创赛科技有限公司
区域：上海市嘉定区
价格：
￥958.0/2500g
￥237.0/500g
￥81.0/100g
￥51.0/25g
联系人：夏言
产品详情：[Perfemiker]三(2-氯乙基)磷酸酯,98%
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