Benzenesulfonamide,4-amino-N-2-pyrazinyl-
名称
[ CAS 号 ]:
116-44-9
[ 英文名 ]:
Benzenesulfonamide,4-amino-N-2-pyrazinyl-
[英文别名 ]:
- SULFAPYRAZINE
- 4-amino-N-pyrazin-2-yl-benzenesulfonamide
- 2-Sulfanilamidopyrazine
- sulfanilic acid pyrazin-2-ylamide
- N(sup 1)-2-Pyrazinylsulfonilamide
- Sulfanilamide,N1-(pyrazinyl)
- Benzenesulfonamide,4-amino-N-pyrazinyl
- Sulfanilsaeure-pyrazin-2-ylamid
- Pyrazine,sulfanilamido
- N1-2-Pyrazinylsulfanilamide
物理化学性质
[ 密度 ]:
1.496g/cm3
[ 沸点 ]:
485.5ºC at 760mmHg
[ 分子式 ]:
C10H10N4O2S
[ 分子量 ]:
250.27700
[ 闪点 ]:
247.4ºC
[ 精确质量 ]:
250.05200
[ PSA ]:
106.35000
[ LogP ]:
2.59460
[ 蒸汽压 ]:
1.41E-09mmHg at 25°C
[ 折射率 ]:
1.679
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DA9550000
- CHEMICAL NAME :
- Benzenesulfonamide, 4-amino-N-pyrazinyl-
- CAS REGISTRY NUMBER :
- 116-44-9
- BEILSTEIN REFERENCE NO. :
- 0235481
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C10-H10-N4-O2-S
- MOLECULAR WEIGHT :
- 250.30
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,354,1943
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,354,1943
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,354,1943 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 45600 mg/kg/22W-C
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes Endocrine - thyroid weight (goiter) Related to Chronic Data - death
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,354,1943
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 45 gm/kg/90D-C
- TOXIC EFFECTS :
- Liver - other changes Kidney, Ureter, Bladder - other changes
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,354,1943
安全信息
[ 海关编码 ]:
2935009090
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[ 海关编码 ]: 2935009090
[ 中文概述 ]:
2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%
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相关化合物
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