环戊酮

环戊酮用途

【用途一】
用作医药及香料工业的原料，也用于橡胶合成及生化制药
【用途二】
本品是一种有机化工原料。是医药及香料工业的原料，可制备新型香料氢茉莉酮酸甲酯，也用于橡胶合成、生化研究和用作杀虫剂。
【用途三】
制药、生物制剂、杀虫剂和橡胶的中间体。

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环戊酮名称

[ CAS 号 ]:
120-92-3

[ 中文名 ]:
环戊酮

[ 英文名 ]:
Cyclopentanone

[中文别名 ]:

環戊酮

[英文别名 ]:

Adipic keyone
MFCD00001409
Cyclopentsnon
Ketocyclopentane
cyclopentan-1-one
Adipinketon
EINECS 204-435-9
Cyclopentanone [UN2245] [Flammable liquid]
Ketopentamethylene
Adipic Ketone

环戊酮物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
130.5±8.0 °C at 760 mmHg

[ 熔点 ]:
-51 °C

[ 分子式 ]:
C₅H₈O

[ 分子量 ]:
84.116

[ 闪点 ]:
30.6±0.0 °C

[ 精确质量 ]:
84.057518

[ PSA ]:
17.07000

[ LogP ]:
0.20

[ 外观性状 ]:
无色液体

[ 蒸汽压 ]:
9.7±0.2 mmHg at 25°C

[ 折射率 ]:
1.457

[ 储存条件 ]:
库房通风低温干燥,与氧化剂、酸类分开存放

[ 稳定性 ]:
Stable. Incompatible with strong reducing agents, strong oxidizing agents, strong bases.

[ 水溶解性 ]:
PRACTICALLY INSOLUBLE

环戊酮MSDS

环戊酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GY4725000

CHEMICAL NAME :: Cyclopentanone

CAS REGISTRY NUMBER :: 120-92-3

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C5-H8-O

MOLECULAR WEIGHT :: 84.13

WISWESSER LINE NOTATION :: L5VTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,271,1979

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,563,1982

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,573,1982

TYPE OF TEST :: Rinsed with water

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,573,1982 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1950 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Behavioral - coma

REFERENCE :: COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. (Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV. Volume(issue)/page/year: 254,2245,1962

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2600 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - coma Lungs, Thorax, or Respiration - other changes

REFERENCE :: AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 50,199,1903

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - changes in motor activity (specific assay) Skin and Appendages - sweating

REFERENCE :: AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 50,199,1903

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 32(10),25,1988

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环戊酮安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H226-H315-H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R10;R36/38

[ 安全声明 (欧洲) ]:
S23

[ 危险品运输编码 ]:
UN 2245 3/PG 3

[ WGK德国 ]:
1

[ RTECS号 ]:
GY4725000

[ 包装等级 ]:
III

[ 危险类别 ]:
3

[ 海关编码 ]:
2914299000

环戊酮合成路线

环戊酮上下游产品

环戊酮上游产品

环戊酮下游产品

环戊酮制备

1.由己二酸在氢氧化钡存在下加热而得。将己二酸与氢氧化钡均匀混合，加热到285-295℃，在此温度下蒸馏出生成的环戊酮。馏出物氯化钙盐析分离出环戊酮，加入量碱液洗除己二酸，再用水洗涤，经无水氯化钙干燥后，分馏，收集128-131℃馏分得成品，产率75-80%。

2.制法：

于装有蒸馏装置、温度计（伸入至接近反应瓶底部）的反应瓶中，加入己二酸（2）200g（1.34mol）与研细的氢氧化钡粉末10g，充分混合均匀。小火慢慢加热至285～290℃，有液体慢慢镏出。保持此温度，直至反应瓶中仅剩少量残渣为止。馏出物用氯化钙饱和，分出有机层，依次用稀碱、饱和食盐水洗涤，无水硫酸镁干燥，分馏，收集128～132℃的馏分，得环戊酮（1）90g，收率78%。

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环戊酮海关

[ 海关编码 ]: 2914299000

[ 中文概述 ]:
2914299000. 其他不含其他含氧基的环烷酮、环烯酮或环萜烯酮. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙酮报明包装

[ Summary ]:
2914299000. other cyclanic, cyclenic or cyclotherpenic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

环戊酮文献

Formation of curcumin nanoparticles by flash nanoprecipitation from emulsions.

J. Colloid. Interface Sci. 434 , 65-70, (2014)

Nanometric particles of a model hydrophobic substance curcumin were prepared by a novel method, namely, flash nanoprecipitation from a coarse oil-in-water emulsion. The method employs turbulent co-mix...

In situ SU-8 silver nanocomposites.

Beilstein J. Nanotechnol. 6 , 1661-5, (2015)

Nanocomposite materials containing metal nanoparticles are of considerable interest in photonics and optoelectronics applications. However, device fabrication of such materials always encounters the c...

Effective Two-Photon Excited Photodynamic Therapy of Xenograft Tumors Sensitized by Water-Soluble Bis(arylidene)cycloalkanone Photosensitizers.

J. Med. Chem. 58 , 7949-58, (2015)

A series of bis(arylidene)cycloalkanone photosensitizers modified by polyethylene glycol (PEG) have been studied for two-photon excited photodynamic therapy (2PE-PDT). As compared with their prototype...

更多文献

环戊酮

环戊酮用途

环戊酮名称

环戊酮物理化学性质

环戊酮MSDS

详细MSDS(安全技术说明书)

环戊酮毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

环戊酮安全信息

环戊酮合成路线

详细合成路线

环戊酮上下游产品

环戊酮上游产品

环戊酮下游产品

环戊酮制备

环戊酮海关

环戊酮文献

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