[(E)-(1-methylpyridin-2-ylidene)methyl]-oxo-azanium; sulfooxymethane
名称
[ CAS 号 ]:
1200-55-1
[ 英文名 ]:
[(E)-(1-methylpyridin-2-ylidene)methyl]-oxo-azanium; sulfooxymethane
[英文别名 ]:
- 2-Formyl-1-methylpyridinium methyl sulfate oxime
- Sulfomethylate de pralidoxime [French]
- Contrastigmine
- Pralidoxime methyl sulfate
- Pyridinium,2-formyl-1-methyl-,methyl sulfate,oxime
- Pyridine-2-aldoxime methylsulfate
- Contrastigmin
- EINECS 214-852-8
物理化学性质
[ 沸点 ]:
189.7ºC at 760 mmHg
[ 分子式 ]:
C8H12N2O5S
[ 分子量 ]:
248.25600
[ 闪点 ]:
68.5ºC
[ 精确质量 ]:
248.04700
[ PSA ]:
111.28000
[ LogP ]:
0.49300
[ 蒸汽压 ]:
0.562mmHg at 25°C
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UU4582000
- CHEMICAL NAME :
- Pyridinium, 2-formyl-1-methyl-, methyl sulfate, oxime
- CAS REGISTRY NUMBER :
- 1200-55-1
- LAST UPDATED :
- 198611
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C7-H9-N2-O.C-H3-O4-S
- MOLECULAR WEIGHT :
- 248.28
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1716 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 15,1146,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 145 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- MEXPAG Medicina Experimentalis. (Basel, Switzerland) V.1-11, 1959-64; V.18-19, 1968-69. For publisher information, see JNMDBO. Volume(issue)/page/year: 8,313,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 686 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 15,1146,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 172 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 15,1146,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 172 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 15,1146,1960
安全信息
[ 海关编码 ]:
2933399090
海关
[ 海关编码 ]: 2933399090
[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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