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1,3,4,6,7,8-六氢-4,6,6,7,8,8-六甲基环五-γ-2-苯并吡喃

用途

【用途一】
广泛用于各种麝香型香料，常以苯甲酸苄酯、邻苯二甲酸二乙酯、十四酸异丙酯或二缩丙二醇等配成约50％的溶液使用

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名称

[ CAS 号 ]:
1222-05-5

[ 中文名 ]:
1,3,4,6,7,8-六氢-4,6,6,7,8,8-六甲基环五-γ-2-苯并吡喃

[ 英文名 ]:
4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene

[中文别名 ]:

[英文别名 ]:

ABBALIDE
Galoxolide
7-acetyl-1,1,3,4,4,6-hexamethyltetraline
EINECS 214-946-9
8-hexamethylcyclopenta[g]-2-benzopyran
MFCD00217003
6-acetyl-1,1,2,4,4,7-hexamethyl-tetralin
Musk50
8-Hexahydro-4
PEARLIDE PURE

物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
326.3±11.0 °C at 760 mmHg

[ 分子式 ]:
C₁₈H₂₆O

[ 分子量 ]:
258.398

[ 闪点 ]:
146.1±15.5 °C

[ 精确质量 ]:
258.198364

[ PSA ]:
9.23000

[ LogP ]:
6.23

[ 外观性状 ]:
无色透明油性液体

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.499

[ 储存条件 ]:
室温

MSDS

详细MSDS(安全技术说明书)

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GY0790000

CHEMICAL NAME :: Cyclopenta(g)-2-benzopyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-

CAS REGISTRY NUMBER :: 1222-05-5

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C18-H26-O

MOLECULAR WEIGHT :: 258.44

WISWESSER LINE NOTATION :: T C566 KOT&TJ D1 D1 E1 E1 F1 F1 M1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,793,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0055 No. of Facilities: 15 (estimated) No. of Industries: 1 No. of Occupations: 16 No. of Employees: 2279 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0055 No. of Facilities: 3202 (estimated) No. of Industries: 10 No. of Occupations: 11 No. of Employees: 32968 (estimated) No. of Female Employees: 20222 (estimated)

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安全信息

[ 符号 ]:

GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H410

[ 警示性声明 ]:
P273-P391-P501

[ 个人防护装备 ]:
Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ 危害码 (欧洲) ]:
Xi: Irritant;N: Dangerous for the environment;

[ 风险声明 (欧洲) ]:
R38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
UN 3082 9 / PGIII

[ WGK德国 ]:
3

[ 海关编码 ]:
2932999099

制备

以六甲基茚满醇和甲醛为原料。经氯甲基化和闭环反应制取。

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海关

[ 海关编码 ]: 2932999099

[ 中文概述 ]:
2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

文献

Metabolism of the polycyclic musk galaxolide and its interference with endogenous and xenobiotic metabolizing enzymes in the European sea bass (Dicentrarchus labrax).

Environ. Pollut. 174 , 214-21, (2013)

This study investigates the metabolism and mode of action of galaxolide (HHCB) in the European sea bass -Dicentrarchus labrax- following a single intraperitoneal injection of 50 mg HHCB/kg body weight...

Simultaneous detection and quantification of select nitromusks, antimicrobial agent, and antihistamine in fish of grocery stores by gas chromatography-mass spectrometry.

Chemosphere 107 , 187-93, (2014)

Continually detected biologically persistent nitromusks; galaxolide (HHCB), tonalide (AHTN) and musk ketone (MK), antimicrobial triclosan (TCS), and antihistamine diphenhydramine (DPH) were examined f...

Levels of synthetic musk fragrances in human milk from three cities in the Yangtze River Delta in Eastern China.

J. Environ. Sci. (China) 23(6) , 983-90, (2011)

Synthetic musks are used as additives in many household products. After absorption into the human body, they accumulate and their concentrations in human milk reflect both the mother and her infant's ...

更多文献

1,3,4,6,7,8-六氢-4,6,6,7,8,8-六甲基环五-γ-2-苯并吡喃

用途

名称

物理化学性质

MSDS

详细MSDS(安全技术说明书)

毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

安全信息

制备

海关

文献

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