普匹西林
普匹西林名称
[ CAS 号 ]:
1245-44-9
[ 中文名 ]:
普匹西林
[ 英文名 ]:
propicillin potassium
[中文别名 ]:
[英文别名 ]:
- propicillin,potassium salt
- baycillinpotassium
- baycillin
- EINECS 214-993-5
- potassiumpropicillin
- PROPICILLIN POTASSIUM
- brocillin
- Potassium procillin
普匹西林物理化学性质
[ 沸点 ]:
675.5ºC at 760mmHg
[ 分子式 ]:
C18H21KN2O5S
[ 分子量 ]:
416.53300
[ 闪点 ]:
362.3ºC
[ 精确质量 ]:
416.08100
[ PSA ]:
124.07000
[ LogP ]:
0.46980
[ 蒸汽压 ]:
3.59E-19mmHg at 25°C
普匹西林毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XH9300000
- CHEMICAL NAME :
- 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6- (2-phenoxybutyramido)-, monopotassium salt
- CAS REGISTRY NUMBER :
- 1245-44-9
- LAST UPDATED :
- 199309
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C18-H21-N2-O5-S.K
- MOLECULAR WEIGHT :
- 416.57
- WISWESSER LINE NOTATION :
- T45 ANV ESTJ CMVY2&OR& F1 F1 GVQ &-KA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,751,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 850 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,751,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 292 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 31,232,1968
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