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甘氨酸-脯氨酸-精氨酸-脯氨酸-氨基化合物

甘氨酸-脯氨酸-精氨酸-脯氨酸-氨基化合物用途

H-Gly-Pro-Arg-Pro-NH2 是一种模拟纤维蛋白链中 N 末端 Gly-Pro-Arg 区域的肽。H-Gly-Pro-Arg-Pro-NH2 防止纤维蛋白聚合。

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甘氨酸-脯氨酸-精氨酸-脯氨酸-氨基化合物名称

[ CAS 号 ]:
126047-75-4

[ 中文名 ]:
H-GLY-PRO-ARG-PRO-NH2

[ 英文名 ]:
H-Gly-Pro-Arg-Pro-NH2 acetate salt

[英文别名 ]:

Gly-Pro-Arg-Pro amide
L-Prolinamide,glycyl-L-prolyl-L-arginyl

甘氨酸-脯氨酸-精氨酸-脯氨酸-氨基化合物生物活性

[ 描述 ]:

H-Gly-Pro-Arg-Pro-NH2 是一种模拟纤维蛋白链中 N 末端 Gly-Pro-Arg 区域的肽。H-Gly-Pro-Arg-Pro-NH2 防止纤维蛋白聚合。

[ 相关类别 ]:

研究领域 >> 心血管疾病

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Mosnier LO, et al. Regulation of fibrinolysis in plasma by TAFI and protein C is dependent on the concentration of thrombomodulin. Thromb Haemost. 2001 Jan;85(1):5-11.

甘氨酸-脯氨酸-精氨酸-脯氨酸-氨基化合物物理化学性质

[ 分子式 ]:
C₁₈H₃₂N₈O₄

[ 分子量 ]:
424.49800

[ 精确质量 ]:
424.25500

[ PSA ]:
200.73000

[ LogP ]:
0.01870

[ 外观性状 ]:
固体

[ 储存条件 ]:
20°C

甘氨酸-脯氨酸-精氨酸-脯氨酸-氨基化合物MSDS

详细MSDS(安全技术说明书)

甘氨酸-脯氨酸-精氨酸-脯氨酸-氨基化合物安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

甘氨酸-脯氨酸-精氨酸-脯氨酸-氨基化合物文献

The synthetic peptide Gly-Pro-Arg-Pro-amide limits the plasmic digestion of fibrinogen in the same fashion as calcium ion.

Protein Sci. 1(12) , 1719-20, (1992)

The benefit-to-risk profile of melagatran is superior to that of hirudin in a rabbit arterial thrombosis prevention and bleeding model.

J. Thromb. Haemost. 1(3) , 587-94, (2003)

Although hirudin is better than heparin at preventing recurrent ischemia in patients with unstable angina, hirudin produces more bleeding. The purpose of this study was to use a rabbit arterial thromb...

Role of the Src family kinase Lyn in TxA2 production, adenosine diphosphate secretion, Akt phosphorylation, and irreversible aggregation in platelets stimulated with gamma-thrombin.

.PubMed ID

Members of the Src family of kinases are abundant in platelets. Although their localization is known, their role(s) in platelet function are not well understood. Lyn is a Src-family kinase that partic...

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