(+/-)-SGCBD01, [(R,S)-4-(4-氯苯基)-2,3,9-三甲基-6H-1-硫杂-5,7,8,9a-四氮杂-环戊环[e]氮杂-6-基]-乙酸叔丁酯, N-(2′,5′-二甲氧基 [1,1'-联苯 ]-4-基)-3-氟-4-吡啶甲酰胺

[ 密度 ]:
1.33±0.1 g/cm3(Predicted)

[ 沸点 ]:
610.4±65.0 °C(Predicted)

[ 分子式 ]:
C₂₃H₂₅ClN₄O₂S

[ 分子量 ]:
456.98800

[ 精确质量 ]:
456.13900

[ PSA ]:
97.61000

[ LogP ]:
4.96690

[ 外观性状 ]:
powder，white to beige

[ 储存条件 ]:
室温

详细MSDS(安全技术说明书)

[ 危险品运输编码 ]:
NONH for all modes of transport

详细合成路线

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Selective inhibition of BET bromodomains.

Nature 468(7327) , 1067-73, (2010)

Epigenetic proteins are intently pursued targets in ligand discovery. So far, successful efforts have been limited to chromatin modifying enzymes, or so-called epigenetic 'writers' and 'erasers'. Pote...

Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer.

Nature 510(7504) , 278-82, (2014)

Men who develop metastatic castration-resistant prostate cancer (CRPC) invariably succumb to the disease. Progression to CRPC after androgen ablation therapy is predominantly driven by deregulated and...

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公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐经理

产品详情：(+/-)-SGCBD01, [(R,S)-4-（4-氯苯基）-2,3,9-三甲基-6H-1-硫杂-5,7,8,9a-四氮杂-环戊环[e]氮杂-6-基]-乙酸叔丁酯, N-(2′,5′-二甲氧基 [1,1'-联苯 ]-4-基）-3-氟-4-吡啶甲酰胺

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公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥1557.0/5mg ￥6265.0/25mg ￥需询单/1g ￥需询单/1g

联系人：阿拉丁

产品详情：(+/-)-JQ1

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(+/-)-SGCBD01, [(R,S)-4-(4-氯苯基)-2,3,9-三甲基-6H-1-硫杂-5,7,8,9a-四氮杂-环戊环[e]氮杂-6-基]-乙酸叔丁酯, N-(2′,5′-二甲氧基 [1,1'-联苯 ]-4-基)-3-氟-4-吡啶甲酰胺供应商