(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) trifluoroacetate salt

用途

(Asn10,Leu11,D-Trp12)-pTH相关蛋白(7-34)酰胺(人、小鼠、大鼠)是一种强效的pTH-1R拮抗剂[1][2]。
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名称

[ CAS 号 ]:
129622-68-0

[ 英文名 ]:
(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) trifluoroacetate salt

[英文别名 ]:

生物活性

[ 描述 ]:

(Asn10,Leu11,D-Trp12)-pTH相关蛋白(7-34)酰胺(人、小鼠、大鼠)是一种强效的pTH-1R拮抗剂[1][2]。

[ 相关类别 ]:

研究领域 >> 代谢疾病

[ 靶点 ]

PTH1R


[参考文献]

[1]. Nutt RF, et al. Removal of partial agonism from parathyroid hormone (PTH)-related protein-(7-34)NH2 by substitution of PTH amino acids at positions 10 and 11. Endocrinology. 1990 Jul;127(1):491-3.  

[2]. Portal-Núñez S, et al. Parathyroid hormone-related protein exhibits antioxidant features in osteoblastic cells through its N-terminal and osteostatin domains. Bone Joint Res. 2018 Jan;7(1):58-68.  

物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 分子式 ]:
C162H254N50O36

[ 分子量 ]:
3478.06

[ 精确质量 ]:
3475.958252

[ LogP ]:
0.51

[ 折射率 ]:
1.664

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相关化合物

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标题：【(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) trifluoroacetate salt】(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) trifluoroacetate salt CAS号:129622-68-0【结构式 性质 活性】-化源网 地址：https://m.chemsrc.com/mip/cas/129622-68-0_1566471.html