9-(p-DIMETHYLAMINOANILINO)ACRIDINE

9-(p-DIMETHYLAMINOANILINO)ACRIDINE名称

[ CAS 号 ]:
13365-38-3

[ 英文名 ]:
9-(p-DIMETHYLAMINOANILINO)ACRIDINE

[英文别名 ]:

ACRIDINE,9-(p-DIMETHYLAMINOANILINO)
9-(p-Dimethylaminoanilino)acridine
WIN 1701
N'-9-Acridinyl-N,N-dimethyl-1,4-benzenediamine
9-((p-(Dimethylamino)phenyl)amino)acridine
9-[(4-Dimethylamino-phenyl)-amino]-acridin
Acridine,9-((p-(dimethylamino)phenyl)amino)

9-(p-DIMETHYLAMINOANILINO)ACRIDINE物理化学性质

[ 密度 ]:
1.229g/cm3

[ 沸点 ]:
490.2ºC at 760 mmHg

[ 分子式 ]:
C₂₁H₁₉N₃

[ 分子量 ]:
313.39600

[ 闪点 ]:
250.3ºC

[ 精确质量 ]:
313.15800

[ PSA ]:
28.16000

[ LogP ]:
5.27060

[ 蒸汽压 ]:
9.34E-10mmHg at 25°C

[ 折射率 ]:
1.748

9-(p-DIMETHYLAMINOANILINO)ACRIDINE毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AR9100000

CHEMICAL NAME :: Acridine, 9-(p-dimethylaminoanilino)-

CAS REGISTRY NUMBER :: 13365-38-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C21-H19-N3

MOLECULAR WEIGHT :: 313.43

WISWESSER LINE NOTATION :: T C666 BNJ IMR DN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80970 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Gastrointestinal - changes in structure or function of salivary glands

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Cardiac - pulse rate

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 35 mg/kg/28D-I

TOXIC EFFECTS :: Cardiac - arrhythmias (including changes in conduction) Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis) Gastrointestinal - changes in structure or function of salivary glands

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 35 mg/kg/28D-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis) Gastrointestinal - changes in structure or function of salivary glands Blood - pigmented or nucleated red blood cells

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 2 umol/L

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,170,1981

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9-(p-DIMETHYLAMINOANILINO)ACRIDINE安全信息

[ 海关编码 ]:
2933990090

9-(p-DIMETHYLAMINOANILINO)ACRIDINE海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%